ID H0XQ20_OTOGA Unreviewed; 416 AA.
AC H0XQ20;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=IF rod domain-containing protein {ECO:0000259|PROSITE:PS51842};
GN Name=LOC100942556 {ECO:0000313|Ensembl:ENSOGAP00000018211.1};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000018211.1, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000018211.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR EMBL; AAQR03161321; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0XQ20; -.
DR STRING; 30611.ENSOGAP00000018211; -.
DR Ensembl; ENSOGAT00000025868.1; ENSOGAP00000018211.1; ENSOGAG00000034036.1.
DR eggNOG; ENOG502QUS8; Eukaryota.
DR GeneTree; ENSGT00940000153309; -.
DR HOGENOM; CLU_012560_8_1_1; -.
DR InParanoid; H0XQ20; -.
DR OMA; REWGHYF; -.
DR TreeFam; TF332742; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR PANTHER; PTHR23239:SF349; KERATIN, TYPE I CYTOSKELETAL 18; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT DOMAIN 66..377
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT COILED 70..104
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 175..202
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 282..369
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 416 AA; 46178 MW; EE655ECF88DCF8E3 CRC64;
SLGSVQAPSY SVRPSSSAAS VYAGAGGSGS QISMSRSTSF QGGWGPGGLA TGMARGLVGI
GGMQIEKETM QELNDCLASY LDKVRNLETD NQRLESKIRE HLEKKGPQVR DWVYYFKTIE
DLRAQIFANS VDNAHIVLQI DNAHLATDDF RVKYETELAM RQSMESDIHG LRKVIDDTNI
TQLQLESEIE ALKEELLFMK KNHEGEVKVL QAQIASSGLT VEVDAPKSQD LSKIMADMRA
QYDELAWKNQ EELAKTWSQQ IEESTSVVTS QFAAVGAAKA MLTELTCTVQ SLEIELDSMR
NQKSRLEGSL REVEAHYAMQ MEQLNGVLLH LESELAQTQA EGQSQAQEYE ALLNIKVKLE
AEIATYRRLL EDGEDFNLGD ALDSSNSMQT IQKTTTCRIV DGKVVSETND TKVLRH
//
