ID H0XS41_OTOGA Unreviewed; 275 AA.
AC H0XS41;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=SRY-box transcription factor 21 {ECO:0000313|Ensembl:ENSOGAP00000018933.1};
GN Name=SOX21 {ECO:0000313|Ensembl:ENSOGAP00000018933.1};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000018933.1, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000018933.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAQR03065480; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003789625.1; XM_003789577.2.
DR AlphaFoldDB; H0XS41; -.
DR STRING; 30611.ENSOGAP00000018933; -.
DR Ensembl; ENSOGAT00000026927.1; ENSOGAP00000018933.1; ENSOGAG00000034277.1.
DR GeneID; 100954699; -.
DR KEGG; oga:100954699; -.
DR CTD; 11166; -.
DR eggNOG; KOG0527; Eukaryota.
DR GeneTree; ENSGT00940000162795; -.
DR HOGENOM; CLU_021123_3_1_1; -.
DR InParanoid; H0XS41; -.
DR OMA; SDSIMGH; -.
DR OrthoDB; 2902801at2759; -.
DR TreeFam; TF351735; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0001942; P:hair follicle development; IEA:Ensembl.
DR GO; GO:0048863; P:stem cell differentiation; IEA:Ensembl.
DR CDD; cd01388; HMG-box_SoxB; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR InterPro; IPR022097; SOX_fam.
DR PANTHER; PTHR10270; SOX TRANSCRIPTION FACTOR; 1.
DR PANTHER; PTHR10270:SF313; TRANSCRIPTION FACTOR SOX-21; 1.
DR Pfam; PF00505; HMG_box; 1.
DR Pfam; PF12336; SOXp; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT DOMAIN 8..76
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 8..76
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
SQ SEQUENCE 275 AA; 28551 MW; 14DCB16E2B97EAF7 CRC64;
MSKPVDHVKR PMNAFMVWSR AQRRKMAQEN PKMHNSEISK RLGAEWKLLT ESEKRPFIDE
AKRLRAMHMK EHPDYKYRPR RKPKTLLKKD KFAFPVPYGL GGVADAEHPA LKAGAGLHAG
AGGGLVPESL LANPEKAAAA AAAAAARVFF PQSAAAAAAA AAAAAGSPYS LLDLGSKMAE
ISSSSSVLPY ASSLGYPTAG AGAFHGAAAA AAAAAAAAGG HTHSHPSPGN PGYMIPCNCS
AWPSPGLQPP LAYILLPGMG KPQLDPYPAA YAAAL
//
