ID H0XSY6_OTOGA Unreviewed; 251 AA.
AC H0XSY6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Folate receptor beta {ECO:0000313|Ensembl:ENSOGAP00000019228.1};
GN Name=FOLR2 {ECO:0000313|Ensembl:ENSOGAP00000019228.1};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000019228.1, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000019228.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the folate receptor family.
CC {ECO:0000256|ARBA:ARBA00007932}.
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DR EMBL; AAQR03001293; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03001294; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012669657.1; XM_012814203.1.
DR AlphaFoldDB; H0XSY6; -.
DR STRING; 30611.ENSOGAP00000019228; -.
DR Ensembl; ENSOGAT00000032632.1; ENSOGAP00000019228.1; ENSOGAG00000031929.1.
DR GeneID; 100951286; -.
DR KEGG; oga:100951286; -.
DR eggNOG; KOG3656; Eukaryota.
DR GeneTree; ENSGT00950000183144; -.
DR HOGENOM; CLU_070826_1_1_1; -.
DR InParanoid; H0XSY6; -.
DR OMA; RKWTDVY; -.
DR OrthoDB; 2905009at2759; -.
DR TreeFam; TF328532; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0009897; C:external side of plasma membrane; IEA:Ensembl.
DR GO; GO:0005542; F:folic acid binding; IEA:Ensembl.
DR GO; GO:0061714; F:folic acid receptor activity; IEA:Ensembl.
DR GO; GO:0008284; P:positive regulation of cell population proliferation; IEA:Ensembl.
DR InterPro; IPR004269; Folate_rcpt.
DR InterPro; IPR018143; Folate_rcpt-like.
DR PANTHER; PTHR10517; FOLATE RECEPTOR; 1.
DR PANTHER; PTHR10517:SF8; FOLATE RECEPTOR BETA; 1.
DR Pfam; PF03024; Folate_rec; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..251
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003546359"
FT DOMAIN 30..205
FT /note="Folate receptor-like"
FT /evidence="ECO:0000259|Pfam:PF03024"
SQ SEQUENCE 251 AA; 28677 MW; C2AF2E14E09900DC CRC64;
MAWKLMLLLL LLAWVAPTFS TKGRTNLLNV CMDAKHHKTK PGPEDKLHDQ CSPWRKNACC
SVNTSQELHK DTSRLYNFNW DHCGKMEPAC KRHFIQDTCL YECSPNLGPW IQQVDQSWRK
ERFLDVPLCK DDCQQWWEAC RTSYTCKSNW HKGWDWSSGV NKCPAGTTCR TFESYFPTPA
ALCEGLWSHS YKVSNYSQGS GRCIQMWFDP AQGNPNEEVA KFYAEAMNAG AMPQGTGTLL
FSLAVMLQLP G
//
