ID H0XW71_OTOGA Unreviewed; 500 AA.
AC H0XW71;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Zinc finger C3HC-type containing 1 {ECO:0000313|Ensembl:ENSOGAP00000020364.1};
GN Name=ZC3HC1 {ECO:0000313|Ensembl:ENSOGAP00000020364.1};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000020364.1, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000020364.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; AAQR03184784; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03184785; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03184786; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03184787; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03184788; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03184789; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03184790; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03184791; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03184792; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03184793; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0XW71; -.
DR STRING; 30611.ENSOGAP00000020364; -.
DR Ensembl; ENSOGAT00000031253.1; ENSOGAP00000020364.1; ENSOGAG00000026193.1.
DR eggNOG; KOG4765; Eukaryota.
DR GeneTree; ENSGT00390000006086; -.
DR HOGENOM; CLU_052185_0_0_1; -.
DR InParanoid; H0XW71; -.
DR OMA; EWCPWIS; -.
DR TreeFam; TF314674; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0031965; C:nuclear membrane; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0019901; F:protein kinase binding; IEA:Ensembl.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IEA:Ensembl.
DR InterPro; IPR013909; NIPA/Rsm1_C.
DR InterPro; IPR012935; Znf_C3HC-like.
DR PANTHER; PTHR15835; NUCLEAR-INTERACTING PARTNER OF ALK; 1.
DR PANTHER; PTHR15835:SF6; ZINC FINGER C3HC-TYPE PROTEIN 1; 1.
DR Pfam; PF08600; Rsm1; 2.
DR Pfam; PF07967; zf-C3HC; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 73..197
FT /note="C3HC-type"
FT /evidence="ECO:0000259|Pfam:PF07967"
FT DOMAIN 246..291
FT /note="Nuclear-interacting partner of ALK/Rsm1-like C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08600"
FT DOMAIN 413..463
FT /note="Nuclear-interacting partner of ALK/Rsm1-like C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08600"
FT REGION 35..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 298..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 435..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..73
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 324..357
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 402..418
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 500 AA; 55244 MW; C44E00269B16F24A CRC64;
MAAPSEGQAF VAGIDNNWGT VVRSPEGTPQ KIRQLIDEGI APEEGGADAK DTSATSQSVN
GSPQAEQPPL ESTSKEAFFN RVETFSISFF TSLPLITLLC LFHGLVTVTC FQLKCHVTNS
SVCTLLFQNL DFDADKERCA ELKKALCTAH EKFCFWPDSP SPDRFGMLPL DEPAILVSEF
LDRFQSLCHL DLQLPSLRPE DLKNMCLTED KISLLLHLLE DELDHRTDER KTTTKLGSDI
QVHVTACILS VCGWAYSSSL EPMQLSLITC SQCMRKVGLW GFQQIESSMT DLDTCFGLTS
SPIPGPEGRP ERFPLVPESP RRMMTRSQDA TFSPGSEQAE KSPGPIVSRT RSWDSSSPVD
RPEPEAASPT TRTRPVTRRM GTGDTTGLEV PSSPLRRAKR ARLCSSSSSD TSSRSFFDPT
SQHRDWCPWV NVTSGKETRE NGGAEPNAKA PSEPGWKAVL TILLAHKQSN QPAETDSMSL
SEKSRKVFRI FRQWESLCSS
//
