ID H0XWT6_OTOGA Unreviewed; 432 AA.
AC H0XWT6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Adenosine 3'-phospho 5'-phosphosulfate transporter 1 {ECO:0000256|ARBA:ARBA00039668};
GN Name=SLC35B2 {ECO:0000313|Ensembl:ENSOGAP00000020579.1};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000020579.1, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000020579.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleotide-sugar transporter family. SLC35B
CC subfamily. {ECO:0000256|ARBA:ARBA00010694}.
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DR EMBL; AAQR03061274; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0XWT6; -.
DR STRING; 30611.ENSOGAP00000020579; -.
DR Ensembl; ENSOGAT00000033142.1; ENSOGAP00000020579.1; ENSOGAG00000029873.1.
DR eggNOG; KOG1581; Eukaryota.
DR GeneTree; ENSGT00940000157927; -.
DR HOGENOM; CLU_036019_3_1_1; -.
DR InParanoid; H0XWT6; -.
DR OMA; KIMTQHY; -.
DR OrthoDB; 1445334at2759; -.
DR TreeFam; TF105926; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:Ensembl.
DR GO; GO:0046964; F:3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0030206; P:chondroitin sulfate biosynthetic process; IEA:Ensembl.
DR InterPro; IPR013657; SCL35B1-4/HUT1.
DR PANTHER; PTHR10778:SF13; ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 1; 1.
DR PANTHER; PTHR10778; SOLUTE CARRIER FAMILY 35 MEMBER B; 1.
DR Pfam; PF08449; UAA; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..432
FT /note="Adenosine 3'-phospho 5'-phosphosulfate transporter
FT 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003545806"
FT TRANSMEM 34..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 154..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 364..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 393..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 432 AA; 47464 MW; 8FEFA6D7B15A8C39 CRC64;
MDARWWAVVV LAALPSLGAG GETPEAPPES WTQLWFFRFL VNAAGYASFM VPGYLLVQYF
RRKNYLETGR GLCFPLVKAC VFGNEPKASE EGPLAPRTET SETTPMWQAL KLLFCAVGLQ
VSYLTWGVLQ ERVMTRSYGA TATSPGEHFT DSQFLVLMNR VLALIVAGFA CILCKQPRHG
APMYRYSFAS LSNVLSSWCQ YEALKFVSFP TQVLAKASKV IPVMLMGKLV SRRSYEHWEY
LTAGLISIGV SMFLLSSGPE PRSSPATTLS GLILLAGYIA FDSFTSNWQD ALFAYKMSSV
QMMFGVNFFS CLFTVGSLLE QGALLEGTHF MGRHSEFAAH ALLLSVCSAC GQLFIFYTIG
QFGAAAFTII MTLRQAFAIL LSCLLYGHTV TVVGGLGVAV VFTALLLRVY ARGRLKQRGK
KAVPNESPVQ KV
//
