ID   H0XXK3_OTOGA            Unreviewed;       404 AA.
AC   H0XXK3;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   SubName: Full=F-box protein 22 {ECO:0000313|Ensembl:ENSOGAP00000020846.1};
GN   Name=FBXO22 {ECO:0000313|Ensembl:ENSOGAP00000020846.1};
OS   Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC   Galagidae; Otolemur.
OX   NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000020846.1, ECO:0000313|Proteomes:UP000005225};
RN   [1] {ECO:0000313|Proteomes:UP000005225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA   Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA   Walker B.J., Sharpe T., Hall G.;
RT   "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSOGAP00000020846.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AAQR03026638; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAQR03026639; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_003784598.1; XM_003784550.2.
DR   AlphaFoldDB; H0XXK3; -.
DR   STRING; 30611.ENSOGAP00000020846; -.
DR   Ensembl; ENSOGAT00000025862.1; ENSOGAP00000020846.1; ENSOGAG00000030630.1.
DR   GeneID; 100967054; -.
DR   KEGG; oga:100967054; -.
DR   CTD; 26263; -.
DR   eggNOG; ENOG502QSZ2; Eukaryota.
DR   GeneTree; ENSGT00390000013049; -.
DR   HOGENOM; CLU_042854_0_0_1; -.
DR   InParanoid; H0XXK3; -.
DR   OMA; PKGCDIM; -.
DR   OrthoDB; 3679169at2759; -.
DR   TreeFam; TF328809; -.
DR   Proteomes; UP000005225; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR   GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR   GO; GO:0009267; P:cellular response to starvation; IEA:Ensembl.
DR   GO; GO:0006913; P:nucleocytoplasmic transport; IEA:Ensembl.
DR   GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR   GO; GO:0000209; P:protein polyubiquitination; IEA:Ensembl.
DR   GO; GO:0048742; P:regulation of skeletal muscle fiber development; IEA:Ensembl.
DR   CDD; cd22097; F-box_FBXO22; 1.
DR   Gene3D; 1.20.1280.50; -; 1.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR019494; FIST_C.
DR   PANTHER; PTHR14939; F-BOX ONLY PROTEIN 22; 1.
DR   PANTHER; PTHR14939:SF5; F-BOX ONLY PROTEIN 22; 1.
DR   Pfam; PF12937; F-box-like; 1.
DR   Pfam; PF10442; FIST_C; 1.
DR   SMART; SM01204; FIST_C; 1.
DR   SUPFAM; SSF81383; F-box domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT   DOMAIN          233..367
FT                   /note="FIST C-domain"
FT                   /evidence="ECO:0000259|SMART:SM01204"
SQ   SEQUENCE   404 AA;  44499 MW;  CEF719727F4EEC6E CRC64;
     MEPVGGGGDR CGSSSADPRS TFVLSNLAEV VERVLTFLPA KALLRVAGVC RLWRECVRRV
     LRTHRSVTWI SAGLAEAGHL EGHCLVRVAA EELENVRILP HTVLYMADSE TFINLEECRG
     HKRARKRTSM ETAFALEKLF PKQCQILGIV TPGIVVTPMG SGSNRPQEIE IGESGFALLF
     PQIEGIKIQP FHFTKDPKKL TIERHQLTEV GLIDNPELRV VLIFGYNCCK MGASNYLHRV
     VSSFSDMNII LAGGQVDNLS SLTSQKNPVD LDATGVVGLS FSGLRIQSAT VLLNEDVTDE
     KSAEAAMQRL KAANIPEQNT IGFMFACVGR GFQYYRAKGN VEADAFRKFF PSVPLFGFFG
     NGEIGCDRIV TGNFILRKCN EVKDDDLFHS YTTIMALIHL GSSK
//