ID H0XY97_OTOGA Unreviewed; 628 AA.
AC H0XY97;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=Tripartite motif containing 80 {ECO:0008006|Google:ProtNLM};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000021090.1, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000021090.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; AAQR03041593; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03041594; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0XY97; -.
DR STRING; 30611.ENSOGAP00000021090; -.
DR Ensembl; ENSOGAT00000028428.1; ENSOGAP00000021090.1; ENSOGAG00000024956.1.
DR eggNOG; KOG2177; Eukaryota.
DR GeneTree; ENSGT00940000162951; -.
DR HOGENOM; CLU_013137_0_2_1; -.
DR InParanoid; H0XY97; -.
DR OMA; MVACFTQ; -.
DR TreeFam; TF351086; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR CDD; cd19802; Bbox1_TRIM8-like; 1.
DR CDD; cd19769; Bbox2_TRIM16-like; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 4.10.830.40; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR PANTHER; PTHR25465:SF34; TRIPARTITE MOTIF-CONTAINING 80; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Immunity {ECO:0000256|ARBA:ARBA00022859};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 74..118
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 209..249
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 427..628
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
SQ SEQUENCE 628 AA; 71597 MW; AF4ACC71545F0DC0 CRC64;
SKQQSKGKVR RRSSSYKHRA AKYLTFSDMK RVSHTVQDLV PALQTPAQPS RPPQGQLLKS
NNSNLRSFED QVLCPICLEV FHNPVTTACG HNFCMTCLQG FWDHQTAMGE TLYCPQCREN
FPSRPRLCKN VILGEMVACF VQARGQAMGS LWNMAGPRDV PCDFCSPPKL KAVKSCLQCM
ASLCEKHLHS HFEDELFQDH QLLEPVWDLK TRLCRKHRKL RQLYCRSEDC CLCSGCLLEG
HKNHDTTPLE EERARQEVEV RKVQANVENQ MLMITSDSQK QREHAAFLSK LIQTIRNEVN
TCFSEIIQEV KQLKIKVLDF VDKEESAALE KLSSSIQQSH TQLRKLEGES VWLHNLLSNR
SDQQFLQELP RLKVFPGCME PLMGIHCEET QSFLQLPETL AKLQTRLMDM GLSFINQLLL
KGIKMSSYEV LPPAVDRKTL LKYYCNLNFD PSTASEELFL FKETYSVLNL GILLEPSDMG
GPLPGFQQWP QVLCSRGLSE GRHYWEAEVS NSWVCLGVTY RRSPPLNGPP RRNIVYLLGR
NPHSWCLEWD SLKFSVWHNN TQTVLHGVYH RTLGVSLDCT TGCLSFYGLG NGGVSLIYRF
LTRFLEPLYP AVMVSSGASV TLKQCPEA
//
