ID H0XZR6_OTOGA Unreviewed; 213 AA.
AC H0XZR6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Nucleic acid binding protein 2 {ECO:0000313|Ensembl:ENSOGAP00000021609.1};
GN Name=NABP2 {ECO:0000313|Ensembl:ENSOGAP00000021609.1};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000021609.1, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000021609.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SOSS-B family. SOSS-B1 subfamily.
CC {ECO:0000256|ARBA:ARBA00038163}.
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DR EMBL; AAQR03076889; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAQR03076890; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; H0XZR6; -.
DR STRING; 30611.ENSOGAP00000021609; -.
DR Ensembl; ENSOGAT00000025171.1; ENSOGAP00000021609.1; ENSOGAG00000026514.1.
DR eggNOG; KOG3416; Eukaryota.
DR GeneTree; ENSGT00940000161079; -.
DR HOGENOM; CLU_102724_0_1_1; -.
DR InParanoid; H0XZR6; -.
DR OMA; QSKAAQN; -.
DR TreeFam; TF313902; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0000781; C:chromosome, telomeric region; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0035861; C:site of double-strand break; IEA:Ensembl.
DR GO; GO:0070876; C:SOSS complex; IEA:Ensembl.
DR GO; GO:0070182; F:DNA polymerase binding; IEA:Ensembl.
DR GO; GO:0098505; F:G-rich strand telomeric DNA binding; IEA:Ensembl.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:Ensembl.
DR GO; GO:0070200; P:establishment of protein localization to telomere; IEA:Ensembl.
DR GO; GO:0044818; P:mitotic G2/M transition checkpoint; IEA:Ensembl.
DR GO; GO:1904355; P:positive regulation of telomere capping; IEA:Ensembl.
DR GO; GO:0010212; P:response to ionizing radiation; IEA:Ensembl.
DR CDD; cd04491; SoSSB_OBF; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR048970; Ssb-like_OB.
DR PANTHER; PTHR13356; OB FOLD NUCLEIC ACID BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR13356:SF3; SOSS COMPLEX SUBUNIT B1; 1.
DR Pfam; PF21473; Ssb-like_OB; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225}.
FT DOMAIN 11..92
FT /note="Single-stranded DNA binding protein Ssb-like OB
FT fold"
FT /evidence="ECO:0000259|Pfam:PF21473"
FT REGION 110..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 110..133
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..158
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 172..188
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 213 AA; 22639 MW; DFFE6E3A2640E640 CRC64;
MTTETFVKDI KPGLKNLNLI FIVLETGRVT KTKDGHEVRT CKVADKTGSI NISVWDDVGN
LIQPGDIIRL TKGYASVFKG CLTLYTGRGG DLQKIGEFCM VYSEVPNFSE PNPEYSTQQA
PNKVVQNDSS PTTPQPTTGP PATSPELASE SQNGNGLSAP PGPGGGSHPP HAPSHTPSTR
ITRSQPNHTP AGPPGPSNNP VSNGKETRRS SKR
//
