ID H0Y0D6_OTOGA Unreviewed; 618 AA.
AC H0Y0D6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Transmembrane protein 200C {ECO:0000313|Ensembl:ENSOGAP00000021829.1};
GN Name=TMEM200C {ECO:0000313|Ensembl:ENSOGAP00000021829.1};
OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lorisiformes;
OC Galagidae; Otolemur.
OX NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000021829.1, ECO:0000313|Proteomes:UP000005225};
RN [1] {ECO:0000313|Proteomes:UP000005225}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA Walker B.J., Sharpe T., Hall G.;
RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSOGAP00000021829.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMEM200 family.
CC {ECO:0000256|ARBA:ARBA00005308}.
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DR EMBL; AAQR03086754; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003792063.1; XM_003792015.2.
DR AlphaFoldDB; H0Y0D6; -.
DR Ensembl; ENSOGAT00000025445.1; ENSOGAP00000021829.1; ENSOGAG00000027984.1.
DR GeneID; 100942930; -.
DR KEGG; oga:100942930; -.
DR CTD; 645369; -.
DR eggNOG; KOG4823; Eukaryota.
DR GeneTree; ENSGT00530000063698; -.
DR HOGENOM; CLU_030031_0_0_1; -.
DR InParanoid; H0Y0D6; -.
DR OMA; CSNKGYT; -.
DR OrthoDB; 5309875at2759; -.
DR TreeFam; TF332635; -.
DR Proteomes; UP000005225; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR018787; DUF2371_TMEM200.
DR PANTHER; PTHR31815; AGAP005329-PA; 1.
DR PANTHER; PTHR31815:SF2; TRANSMEMBRANE PROTEIN 200C; 1.
DR Pfam; PF10177; DUF2371; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 53..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 13..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 83..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 290..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 348..368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 387..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 430..590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 477..491
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 524..550
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 567..590
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 618 AA; 63975 MW; B1A6122D3FABF859 CRC64;
MIATGGLLRI SARKQDPLRP PSQVPKRKRK ARKRRKNDVV VVKGKLKLCS ISGLVALCGI
LVLLVGIAMA VVGYWPKANG ASKEAGKQLP PAGNGHRVPT KVNISNSGSK NRSKSHSGTP
GSVNSSSVGT PKGTPPARPA APPSSSTSVG FFFRIFSGYL HSDKLKVFGP LIMGIGIFLF
ICANAVLHEN RDKKTKIINL RDLYSTVIDV HSLRAKDLAA AAAAAAAAAA SSSSSAPTSA
PPGAAPLNGF LSYVQSRGLE LKPGSCCSSG DAFGAGAMLA KGSWPHPAAL SGGGARGAAS
PPDLASSPRC PREPPSLAEA VYSIYCERSG VASRRRAAAA TAATAAASGC SSPAPCSPPE
SWGRQSTASS LVGSSLSVFA LLPLQGDRDG DAEGASCSWQ RPPGERGPRE IPRGELDLSL
TSLRGAEGGA RWARSELEEP EGAVAVRTAR GQGCRPPRTG RYAALRRRST SGLPDYRAPP
SPEPPPSPGP DLDLSLLAET ASPSPPLRLE DSPPARRDSG SSRSDEPSSS NKGYTPLQEA
GTSLESVVDT VASERQDCEA ATALGAEQST PEGTSQEPPS AEQPQPAQRQ FTNKEKLFMI
SRSHAIGVEE GELESTGT
//
