GenomeNet

Database: UniProt
Entry: H0Y1Z7_OTOGA
LinkDB: H0Y1Z7_OTOGA
Original site: H0Y1Z7_OTOGA 
ID   H0Y1Z7_OTOGA            Unreviewed;       825 AA.
AC   H0Y1Z7;
DT   22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT   22-FEB-2012, sequence version 1.
DT   05-JUN-2019, entry version 48.
DE   SubName: Full=ADAM metallopeptidase domain 29 {ECO:0000313|Ensembl:ENSOGAP00000022390};
GN   Name=ADAM29 {ECO:0000313|Ensembl:ENSOGAP00000022390};
OS   Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini;
OC   Lorisiformes; Galagidae; Otolemur.
OX   NCBI_TaxID=30611 {ECO:0000313|Ensembl:ENSOGAP00000022390, ECO:0000313|Proteomes:UP000005225};
RN   [1] {ECO:0000313|Ensembl:ENSOGAP00000022390}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The Broad Institute Genome Sequencing Platform;
RA   Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B.,
RA   Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N.,
RA   Walker B.J., Sharpe T., Hall G.;
RT   "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby).";
RL   Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSOGAP00000022390}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2012) to UniProtKB.
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DR   EMBL; AAQR03095643; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 30611.ENSOGAP00000022390; -.
DR   Ensembl; ENSOGAT00000015488; ENSOGAP00000022390; ENSOGAG00000015487.
DR   eggNOG; KOG3607; Eukaryota.
DR   eggNOG; ENOG410XX2M; LUCA.
DR   GeneTree; ENSGT00940000163394; -.
DR   InParanoid; H0Y1Z7; -.
DR   OMA; CHCNYLW; -.
DR   TreeFam; TF314733; -.
DR   Proteomes; UP000005225; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   CDD; cd04269; ZnMc_adamalysin_II_like; 1.
DR   Gene3D; 3.40.390.10; -; 1.
DR   Gene3D; 4.10.70.10; -; 1.
DR   InterPro; IPR006586; ADAM_Cys-rich.
DR   InterPro; IPR018358; Disintegrin_CS.
DR   InterPro; IPR001762; Disintegrin_dom.
DR   InterPro; IPR036436; Disintegrin_dom_sf.
DR   InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR   InterPro; IPR001590; Peptidase_M12B.
DR   InterPro; IPR002870; Peptidase_M12B_N.
DR   InterPro; IPR034027; Reprolysin_adamalysin.
DR   Pfam; PF08516; ADAM_CR; 1.
DR   Pfam; PF00200; Disintegrin; 1.
DR   Pfam; PF01562; Pep_M12B_propep; 1.
DR   Pfam; PF01421; Reprolysin; 1.
DR   PRINTS; PR00289; DISINTEGRIN.
DR   SMART; SM00608; ACR; 1.
DR   SMART; SM00050; DISIN; 1.
DR   SUPFAM; SSF57552; SSF57552; 1.
DR   PROSITE; PS50215; ADAM_MEPRO; 1.
DR   PROSITE; PS00427; DISINTEGRIN_1; 1.
DR   PROSITE; PS50214; DISINTEGRIN_2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005225};
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00068,
KW   ECO:0000256|SAAS:SAAS00877335};
KW   Membrane {ECO:0000256|SAAS:SAAS01078504, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005225};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAAS:SAAS01078486,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS01078482,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    825       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003546322.
FT   TRANSMEM    681    699       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      198    390       Peptidase M12B. {ECO:0000259|PROSITE:
FT                                PS50215}.
FT   DOMAIN      397    483       Disintegrin. {ECO:0000259|PROSITE:
FT                                PS50214}.
FT   REGION      708    825       Disordered. {ECO:0000256|MobiDB-lite:
FT                                H0Y1Z7}.
FT   COMPBIAS    726    793       Polar. {ECO:0000256|MobiDB-lite:H0Y1Z7}.
FT   COMPBIAS    808    825       Polar. {ECO:0000256|MobiDB-lite:H0Y1Z7}.
FT   DISULFID    455    475       {ECO:0000256|PROSITE-ProRule:PRU00068}.
SQ   SEQUENCE   825 AA;  92809 MW;  04937CC5F7E591E7 CRC64;
     LKILVLLHWL GVFLFCSGHT EDEHPRYHNP PEVVIPLKVT GTARGKKTPG WLSYSLHFGG
     QEHIIHLRVK RILLSPHLSV FTYTDQGAVL EDQPFVQNDC YYHGHVEGDP ESLVALSTCF
     GGFQGILQIS DIVYEIKPMM FSTTFEHLVY IVDGKEAQFP TVRSGLMKNE ISCHIQFQET
     NESSRYPTSY EGWWVHIRII EFVIVADSYL YKRYERNESK LMEDLYVLNN IVNSIHLVIG
     NRILLVNLEI WTEKNPFVVD DPNFSAPRFC QWKWTTIYAE LRHDIAHLFM NRELRGLSGS
     GLTRGSCTGL RNCAIITFWN KTLGRSAIAT AHHLGHNVGM PHDRPTCKCA HPKCIMHEHN
     PPTTKFSNCS YDYFYQYTVQ KTKCLLEHFH TKDIFNLKRC GNGVVEGEEQ CDCGVLKHCA
     KDPCCMPDCT LTQGSACAYG LCCKNCQFLP SGELCRKEVN QCDLPEWCNG TSHKCPDDVY
     VEDGIPCNDR SYCYEKRCND RDQHCQQIFG KDAKNAIQSC YKRVNTQGTR VGHCGIKGST
     YVKCGKLDIL CGRLQCENVK ELPSLSDHTT VYLSNFSDAT CWGTDYHIGM TIPDIGDVKD
     GTECGQDHMC IKQHCVHIAF LDSNCSPELC NMRGICNNKH HCHCNYLWDP PHCVMKGYGG
     SVDSGPPPKT ERKKKFCFPC LLVLLILLIL LCCLCFMLCR KKSKKKEIKQ KEVKAKEKPK
     SAVPSRAPSV ASQGEKNVLS APPSRAPSVV SQGEKTMPSA PPSRAPSVVS QGEKNVLSAP
     PSRAPSVVSQ EGKPKQPQKE KEKLQRPPSR APSTQSQGST KMSPA
//
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