ID H0Y9G6_HUMAN Unreviewed; 363 AA.
AC H0Y9G6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE RecName: Full=Large ribosomal subunit protein uL3m {ECO:0000256|ARBA:ARBA00035209};
DE AltName: Full=39S ribosomal protein L3, mitochondrial {ECO:0000256|ARBA:ARBA00035396};
DE Flags: Fragment;
GN Name=MRPL3 {ECO:0000313|Ensembl:ENSP00000424107.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000424107.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000424107.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16641997; DOI=10.1038/nature04728;
RA Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J.,
RA Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P.,
RA Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A.,
RA Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L.,
RA Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G.,
RA Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W.,
RA Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M.,
RA Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P.,
RA Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H.,
RA Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J.,
RA Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W.,
RA Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B.,
RA Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O.,
RA Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X.,
RA Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R.,
RA Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.;
RT "The DNA sequence, annotation and analysis of human chromosome 3.";
RL Nature 440:1194-1198(2006).
RN [2] {ECO:0007829|PubMed:21269460}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Burckstummer T.,
RA Bennett K.L., Superti-Furga G., Colinge J.;
RT "Initial characterization of the human central proteome.";
RL BMC Syst. Biol. 5:17-17(2011).
RN [3] {ECO:0007829|PubMed:25944712}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=25944712;
RA Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M., Ayoub D.,
RA Lane L., Bairoch A., Van Dorsselaer A., Carapito C.;
RT "N-terminome analysis of the human mitochondrial proteome.";
RL Proteomics 15:2519-2524(2015).
RN [4] {ECO:0000313|Ensembl:ENSP00000424107.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL3 family.
CC {ECO:0000256|ARBA:ARBA00006540, ECO:0000256|RuleBase:RU003905}.
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DR EMBL; AC107027; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EPD; H0Y9G6; -.
DR MassIVE; H0Y9G6; -.
DR MaxQB; H0Y9G6; -.
DR PeptideAtlas; H0Y9G6; -.
DR ProteomicsDB; 36023; -.
DR Antibodypedia; 33349; 215 antibodies from 33 providers.
DR Ensembl; ENST00000511168.5; ENSP00000424107.1; ENSG00000114686.9.
DR UCSC; uc062nwa.1; human.
DR HGNC; HGNC:10379; MRPL3.
DR VEuPathDB; HostDB:ENSG00000114686; -.
DR GeneTree; ENSGT00390000011422; -.
DR ChiTaRS; MRPL3; human.
DR Proteomes; UP000005640; Chromosome 3.
DR Bgee; ENSG00000114686; Expressed in secondary oocyte and 214 other cell types or tissues.
DR ExpressionAtlas; H0Y9G6; baseline and differential.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:InterPro.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR000597; Ribosomal_uL3.
DR InterPro; IPR019927; Ribosomal_uL3_bac/org-type.
DR InterPro; IPR019926; Ribosomal_uL3_CS.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR03625; L3_bact; 1.
DR PANTHER; PTHR11229:SF8; 39S RIBOSOMAL PROTEIN L3, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11229; 50S RIBOSOMAL PROTEIN L3; 1.
DR Pfam; PF00297; Ribosomal_L3; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00474; RIBOSOMAL_L3; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:H0Y9G6,
KW ECO:0007829|MaxQB:H0Y9G6};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|RuleBase:RU003905};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980,
KW ECO:0000256|RuleBase:RU003905}.
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSP00000424107.1"
SQ SEQUENCE 363 AA; 40582 MW; 8738431D601A708C CRC64;
XFFPSQRASA GDRSGGHCEN FPTATASTWR WRGDSLKAER QGARKSTHIW LFVRGLHGKS
GTWWDEHLSE ENVPFIKQLV SDEDKAQLAS KLCPLKDEPW PIHPWEPGSF RVGLIALKLG
MMPLWTKDGQ KHVVTLLQVQ DCHVLKYTSK ENCNGKMATL SVGGKTVSRF RKATSILEFY
RELGLPPKQT VKIFNITDNA AIKPGTPLYA AHFRPGQYVD VTAKTIGKGF QGVMKRWGFK
GQPATHGQTK THRRPGAVAT GDIGRVWPGT KMPGKMGNIY RTEYGLKVWR INTKHNIIYV
NGSVPGHKNC LVKVKDSKLP AYKDLGKNLP FPTYFPDGDE EELPEDLYDE NVCQPGAPSI
TFA
//
