ID H0YAQ7_HUMAN Unreviewed; 119 AA.
AC H0YAQ7;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Pleckstrin and Sec7 domain containing 3 {ECO:0000313|Ensembl:ENSP00000427897.1};
DE Flags: Fragment;
GN Name=PSD3 {ECO:0000313|Ensembl:ENSP00000427897.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000427897.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000427897.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16421571; DOI=10.1038/nature04406;
RA Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M.,
RA Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L.,
RA Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S.,
RA Asakawa T., Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A.,
RA Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III,
RA Engels R., Glockner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K.,
RA Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B.,
RA O'Neill K., Parker S.C., Polley A., Raymond C.K., Reichwald K.,
RA Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L.,
RA Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G.,
RA Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W.,
RA Platzer M., Shimizu N., Lander E.S.;
RT "DNA sequence and analysis of human chromosome 8.";
RL Nature 439:331-335(2006).
RN [2] {ECO:0000313|Ensembl:ENSP00000427897.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC009884; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC087821; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC090420; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC100800; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC100849; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC120051; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR MassIVE; H0YAQ7; -.
DR MaxQB; H0YAQ7; -.
DR PeptideAtlas; H0YAQ7; -.
DR ProteomicsDB; 36458; -.
DR Antibodypedia; 9043; 161 antibodies from 22 providers.
DR Ensembl; ENST00000521027.5; ENSP00000427897.1; ENSG00000156011.19.
DR UCSC; uc064krm.1; human.
DR HGNC; HGNC:19093; PSD3.
DR VEuPathDB; HostDB:ENSG00000156011; -.
DR GeneTree; ENSGT00940000156591; -.
DR HOGENOM; CLU_2078381_0_0_1; -.
DR ChiTaRS; PSD3; human.
DR Proteomes; UP000005640; Chromosome 8.
DR Bgee; ENSG00000156011; Expressed in Brodmann (1909) area 23 and 201 other cell types or tissues.
DR ExpressionAtlas; H0YAQ7; baseline and differential.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR10663:SF337; PH AND SEC7 DOMAIN-CONTAINING PROTEIN 3; 1.
DR Pfam; PF01369; Sec7; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:H0YAQ7,
KW ECO:0007829|MaxQB:H0YAQ7};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 31..88
FT /note="SEC7"
FT /evidence="ECO:0000259|Pfam:PF01369"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSP00000427897.1"
SQ SEQUENCE 119 AA; 13280 MW; 0F7C766D3F9C4F85 CRC64;
XLEAHSEMGS TEILEKETPE NLSNGTSSNV EAAKRLAKRL YQLDRFKRSD VAKHLGKNNE
FSKLVAEEYL KFFDFTGMTL DQSLRVSLCH PGWSAVAPSW LTATSTSQVQ AVLLNQPPE
//
