ID H0YE79_HUMAN Unreviewed; 70 AA.
AC H0YE79;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Activating signal cointegrator 1 complex subunit 1 {ECO:0000313|Ensembl:ENSP00000435191.1};
DE Flags: Fragment;
GN Name=ASCC1 {ECO:0000313|Ensembl:ENSP00000435191.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000435191.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000435191.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15164054; DOI=10.1038/nature02462;
RA Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L.,
RA Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K.,
RA Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L.,
RA Taylor A., Battles J., Bird C.P., Ainscough R., Almeida J.P.,
RA Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J.,
RA Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y.,
RA Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P.,
RA Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N.,
RA Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A.,
RA Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C.,
RA Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D.,
RA Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C.,
RA Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K.,
RA Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A.,
RA Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S.,
RA McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S.,
RA Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V.,
RA Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A.,
RA Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M.,
RA Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A.,
RA Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P.,
RA Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y.,
RA Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D.,
RA Durbin R., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.;
RT "The DNA sequence and comparative analysis of human chromosome 10.";
RL Nature 429:375-381(2004).
RN [2] {ECO:0000313|Ensembl:ENSP00000435191.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AC022392; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AL607035; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR MassIVE; H0YE79; -.
DR MaxQB; H0YE79; -.
DR PeptideAtlas; H0YE79; -.
DR ProteomicsDB; 37641; -.
DR Ensembl; ENST00000461369.6; ENSP00000435191.1; ENSG00000138303.19.
DR UCSC; uc057txp.1; human.
DR HGNC; HGNC:24268; ASCC1.
DR VEuPathDB; HostDB:ENSG00000138303; -.
DR GeneTree; ENSGT00390000018119; -.
DR HOGENOM; CLU_2782424_0_0_1; -.
DR ChiTaRS; ASCC1; human.
DR Proteomes; UP000005640; Chromosome 10.
DR Bgee; ENSG00000138303; Expressed in calcaneal tendon and 199 other cell types or tissues.
DR ExpressionAtlas; H0YE79; baseline and differential.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR InterPro; IPR004088; KH_dom_type_1.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR Pfam; PF00013; KH_1; 1.
DR SUPFAM; SSF54791; Eukaryotic type KH-domain (KH-domain type I); 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|MaxQB:H0YE79,
KW ECO:0007829|PeptideAtlas:H0YE79};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 29..63
FT /note="K Homology"
FT /evidence="ECO:0000259|Pfam:PF00013"
FT REGION 50..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSP00000435191.1"
SQ SEQUENCE 70 AA; 8118 MW; F668E696044AB573 CRC64;
XLIHLNTSND CGFQKITLDC QNIYTWKSRH IVGKRGDTRK KIEMETKTSI SIPKPGQDGE
IEKSEKEMIW
//
