ID H0YH70_HUMAN Unreviewed; 95 AA.
AC H0YH70;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 22-FEB-2012, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Multiple PDZ domain crumbs cell polarity complex component {ECO:0000313|Ensembl:ENSP00000446298.1};
DE Flags: Fragment;
GN Name=MPDZ {ECO:0000313|Ensembl:ENSP00000446298.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000446298.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000446298.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15164053; DOI=10.1038/nature02465;
RA Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L.,
RA Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R.,
RA Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S.,
RA Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K.,
RA Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y.,
RA Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C.,
RA Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E.,
RA Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M.,
RA Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J.,
RA Frankish A., Frankland J.A., French L., Fricker D.G., Garner P.,
RA Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S.,
RA Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E.,
RA Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D.,
RA Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E.,
RA Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K.,
RA Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S.,
RA Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J.,
RA Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E.,
RA McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V.,
RA Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S.,
RA Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K.,
RA Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J.,
RA Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M.,
RA West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L.,
RA Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.,
RA Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J.,
RA Dunham I.;
RT "DNA sequence and analysis of human chromosome 9.";
RL Nature 429:369-374(2004).
RN [2] {ECO:0007829|PubMed:24275569}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014;
RA Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L.,
RA Ye M., Zou H.;
RT "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver
RT phosphoproteome.";
RL J. Proteomics 96:253-262(2014).
RN [3] {ECO:0000313|Ensembl:ENSP00000446298.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AL161449; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AL162386; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AL353639; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KF458899; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KF458902; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR MassIVE; H0YH70; -.
DR MaxQB; H0YH70; -.
DR PeptideAtlas; H0YH70; -.
DR ProteomicsDB; 38617; -.
DR Ensembl; ENST00000535169.1; ENSP00000446298.1; ENSG00000107186.17.
DR UCSC; uc064sdu.1; human.
DR HGNC; HGNC:7208; MPDZ.
DR VEuPathDB; HostDB:ENSG00000107186; -.
DR GeneTree; ENSGT00940000155586; -.
DR HOGENOM; CLU_2391646_0_0_1; -.
DR ChiTaRS; MPDZ; human.
DR Proteomes; UP000005640; Chromosome 9.
DR Bgee; ENSG00000107186; Expressed in calcaneal tendon and 193 other cell types or tissues.
DR ExpressionAtlas; H0YH70; baseline and differential.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR19964; MULTIPLE PDZ DOMAIN PROTEIN; 1.
DR PANTHER; PTHR19964:SF10; MULTIPLE PDZ DOMAIN PROTEIN; 1.
DR Pfam; PF00595; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:H0YH70,
KW ECO:0007829|MaxQB:H0YH70};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT DOMAIN 44..95
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSP00000446298.1"
SQ SEQUENCE 95 AA; 10406 MW; DB735329AD96A152 CRC64;
XMGSDHTQSS ASKISQDVDK EDEFGYSWKN IRERYGTLTG ELHMIELEKG HSGLGLSLAG
NKDRSRMSVF IVGIDPNGAA GKDGRLQIAD ELLEK
//
