ID H0YSA6_TAEGU Unreviewed; 471 AA.
AC H0YSA6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Abl interactor 1 {ECO:0000313|Ensembl:ENSTGUP00000001166.2};
GN Name=ABI1 {ECO:0000313|Ensembl:ENSTGUP00000001166.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000001166.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000001166.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000001166.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, filopodium
CC {ECO:0000256|ARBA:ARBA00004486}. Cell projection, lamellipodium
CC {ECO:0000256|ARBA:ARBA00004510}.
CC -!- SIMILARITY: Belongs to the ABI family. {ECO:0000256|ARBA:ARBA00010020}.
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DR AlphaFoldDB; H0YSA6; -.
DR STRING; 59729.ENSTGUP00000037341; -.
DR Ensembl; ENSTGUT00000001178.2; ENSTGUP00000001166.2; ENSTGUG00000001133.2.
DR GeneTree; ENSGT00940000154811; -.
DR HOGENOM; CLU_035421_0_0_1; -.
DR TreeFam; TF314303; -.
DR Proteomes; UP000007754; Chromosome 2.
DR GO; GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.
DR GO; GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
DR CDD; cd11971; SH3_Abi1; 1.
DR Gene3D; 6.10.140.1620; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR028457; ABI.
DR InterPro; IPR035725; Abi1_SH3.
DR InterPro; IPR012849; Abl-interactor_HHR_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR000727; T_SNARE_dom.
DR PANTHER; PTHR10460:SF2; ABL INTERACTOR 1; 1.
DR PANTHER; PTHR10460; ABL INTERACTOR FAMILY MEMBER; 1.
DR Pfam; PF07815; Abi_HHR; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS50192; T_SNARE; 1.
PE 3: Inferred from homology;
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 64..126
FT /note="T-SNARE coiled-coil homology"
FT /evidence="ECO:0000259|PROSITE:PS50192"
FT DOMAIN 409..468
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 178..384
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 300..353
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..384
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 471 AA; 51575 MW; 98F042CE3E174E29 CRC64;
MAELQMLLEE EIPSGKRALL ESYQNLTRVA DYCENNYIQI KYIGCSADLL DYRFFQIQAP
DKRKALEETK AYTTQSLASV AYQINALANN VLQLLDIQAS QLRRMESSIN HISQTVDIHK
EKVARREIGI LTTNKNTSRT HKIIAPANME RPVRYIRKPI DYTVLDDVGH GVKWLKAKHG
NNQPARTGTL SRTNPPTQKP PSPPMSGRGT LGRNTPYKTL EPVKPPTVPN DYMTSPARLG
SQHSPGRTAS LNQRPRTHSG SSGGSGSREN SGSSSIGIPI AVPTPSPPTI GPAAPGSAPG
SQYGTMTRQI SRHNSTTSSA SSGGYRRNPS VTAPFSAQPH VNGGPLYSQN SIADSPTPPP
PPPPDEMPMF DDSPPPPPPP PVDYEDEEAA VVQYSDPYAD GDPAWAPKNY IEKVVAIYDY
TKDKDDELSF MEGAIIYVIK KNDDGWYEGV CNRVTGLFPG NYVESIMHYA D
//
