ID H0YSU7_TAEGU Unreviewed; 436 AA.
AC H0YSU7;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=GRAM domain containing 2B {ECO:0000313|Ensembl:ENSTGUP00000001358.2};
GN Name=GRAMD2B {ECO:0000313|Ensembl:ENSTGUP00000001358.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000001358.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000001358.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000001358.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; H0YSU7; -.
DR STRING; 59729.ENSTGUP00000001358; -.
DR Ensembl; ENSTGUT00000001371.2; ENSTGUP00000001358.2; ENSTGUG00000001316.2.
DR GeneTree; ENSGT00940000156980; -.
DR HOGENOM; CLU_050698_1_0_1; -.
DR InParanoid; H0YSU7; -.
DR OMA; CKDSRGN; -.
DR TreeFam; TF332065; -.
DR Proteomes; UP000007754; Chromosome Z.
DR GO; GO:0005881; C:cytoplasmic microtubule; IEA:Ensembl.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR CDD; cd13220; PH-GRAM_GRAMDC; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR46645:SF2; GRAM DOMAIN-CONTAINING PROTEIN 2B; 1.
DR PANTHER; PTHR46645; GRAM DOMAIN-CONTAINING PROTEIN 2B-RELATED; 1.
DR Pfam; PF02893; GRAM; 1.
DR SMART; SM00568; GRAM; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 352..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 115..182
FT /note="GRAM"
FT /evidence="ECO:0000259|SMART:SM00568"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 225..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 296..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..241
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 436 AA; 49305 MW; 92F620151B762FE5 CRC64;
MLKKRSSLDD SVPLSESQNS FQKSSNDTPA SPMESVGSVF ISSDGENGTE EKRKSGKSPT
VSLQTPTSEM EYFDYRKKVD VDRTKSSTDS PVLTIKSDSK IERKKRASNQ LKANAHFHKL
FLDVPIDEPL KQSFTCALQK EILYQGKLFL SENWICFHSK VFGKDTKISI PVLSVTLLKK
TKTALLVPNA LIIATVTDRY MFVSLLSRDT TYKLLKSICT HLDDTSMGNS PNPSSAENSF
RADRPRTLPL DFNEDYSDLD GIVQQRRQEM EESSSTGSQT PELECFQDYH VVETETHLKV
SKPEAKSVRS DAHSKRGPDG KARNSPRNGH SEAFRFLHKV TSQKLLSLNH VLVFYAILVC
VLILSTFYMR YKINVLEERL MSMTAFDSHI KEHQMHQDLG SHLQTNADAL CDELTANLRK
LEKIQNNLQR LLEAGE
//
