ID H0YTL1_TAEGU Unreviewed; 1339 AA.
AC H0YTL1;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Protein phosphatase 1 regulatory subunit 9A {ECO:0000313|Ensembl:ENSTGUP00000001624.2};
GN Name=PPP1R9A {ECO:0000313|Ensembl:ENSTGUP00000001624.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000001624.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000001624.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000001624.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR STRING; 59729.ENSTGUP00000001624; -.
DR Ensembl; ENSTGUT00000001638.2; ENSTGUP00000001624.2; ENSTGUG00000001566.2.
DR GeneTree; ENSGT00940000155538; -.
DR HOGENOM; CLU_007401_0_0_1; -.
DR InParanoid; H0YTL1; -.
DR OMA; CPDGLSQ; -.
DR OrthoDB; 2911512at2759; -.
DR TreeFam; TF105540; -.
DR Proteomes; UP000007754; Chromosome 2.
DR GO; GO:0030864; C:cortical actin cytoskeleton; IEA:Ensembl.
DR GO; GO:0043197; C:dendritic spine; IEA:Ensembl.
DR GO; GO:0030175; C:filopodium; IEA:Ensembl.
DR GO; GO:0007015; P:actin filament organization; IEA:Ensembl.
DR GO; GO:0019722; P:calcium-mediated signaling; IEA:Ensembl.
DR GO; GO:0050804; P:modulation of chemical synaptic transmission; IEA:Ensembl.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR CDD; cd00992; PDZ_signaling; 1.
DR CDD; cd09512; SAM_Neurabin-like; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR040645; Neurabin-1/2_PDZ.
DR InterPro; IPR043446; Neurabin-like.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR16154; NEURABIN; 1.
DR PANTHER; PTHR16154:SF22; NEURABIN-1; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF17817; PDZ_5; 1.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754}.
FT DOMAIN 523..611
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1229..1292
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 174..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 258..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 906..973
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 987..1090
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1128..1194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1292..1339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 619..646
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 699..842
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..54
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 181..204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..304
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..330
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..360
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 389..406
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1008..1022
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1038..1054
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1128..1180
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1292..1333
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1339 AA; 149198 MW; DB103D5675A69B3E CRC64;
MMKTESSGER STLRSASPHR NAYRTEFQAL KSTFDKPKSD GDQKAKEEGE VSQSRGRKYG
SNVNRIKNLF MQMGMEPTES AGVAPKTRGK RGPPSPQRRI RPKEFVEKAD GSIVKLESSV
SERISRFDTI HDGPSYSKFT ETRKMFERNA HEMGHSNRYS PKKEKIISNE LPDEWCSSKS
HRGSTDSLDS LSPRTETVSP TVSQLSAVFE NTDSHNVIVE KSENNEEYSV TGHYPLNLSS
TVTNISSPVA NLEGFSPLKE ASTWSPPAKQ STGVMSVENS EQTNTPSTPR QKVSTGTSAA
SKTTEEIKKT TEASADSVES SATGQQDLVG VFDSERSMDS CARSKSKTET GILVQQKEQS
KHTEGVFDRP DAAELTRNVA SGGDFATDAS ESHYDEESEK DGHEDVNNFQ SSHVYMHSDY
NVYRVRSRYN SDWGETGTEQ DDLDDSDENN CYEPDMEYSE INGLPDEDEI PANRKIQFSR
APIKVFNTYS NEDYDRRNDE VDPVAASAEY ELEKRVEKLE LFPVELEKDE DGLGISIIGM
GVGADAGLEK LGIFVKTVTE GGTAERDGRI QVNDQIVEVD GISLVGVTQN FAATVLRNTK
EKVRFVIGRE KPGQVSEVAQ LISQTLEQER RQRELLEQHY AQYDADDDET GEYATDEEDE
DMGPVLPGGD MAIEVFDLPE NDDMFSPSDV DTSKLAHKFK ELQIKHAVTE AEIQKLKTKL
QAAENEKVRW ELEKTQLQQN IEENKERMMK LESYWIEAQT LCHTVNEHLK ETQSQYQALE
KKYNKAKKLI KDFQQKELDF IKRQEAERKK IEDLEKAHLV EVQGLQARIQ DLEAEVFRLM
KQNGSQVNNN NNIFERQTSF GEVSRGDPVE NLDTKQVTCL DGLSQDFNEA VPETERLDSK
ALKTRAQLSV KNKRQRPSRT RLYDSISSTD GEDSLERKPS HSYSSPMHIS KSPLPLCMRA
SSPASDSGAS SLSPVASSAA ISLDNLSENQ EEEQHHKGGV LSPYARGDTP LSSPSKSGHS
SEASPLHHPA GRNILQDKDG ATSAQAARTT SPTIGHTEKL KRKLADLGAP LRRSSSKGKK
RKEKEAIRVA CGSRTVREML QKPANTKSLA ERSSSLPHCV PFTWYGESGK GSNSSSNLPS
PTSSTEPSSE NLSPAKKGSK NFTFNDDFSP SSTSSADLSG LGAEPKTPGF SHSLALSSDE
SLDMIDDEIL DDGQSPKHSQ CQSRAVHEWS VQQVSHWLMS LNLEQYVSEF SAQNINGEHL
LQLDGSKLKA LGMTSSQDRA IIKRKLKEMK ASLEKARKAQ EKMEKQREKL RKKEQEQLQR
RSKKTDKCSS DATEGTNEQ
//
