ID H0YV82_TAEGU Unreviewed; 986 AA.
AC H0YV82;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=Unconventional myosin-Id {ECO:0000256|ARBA:ARBA00039641};
GN Name=MYO1D {ECO:0000313|Ensembl:ENSTGUP00000002203.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000002203.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000002203.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000002203.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, dendrite
CC {ECO:0000256|ARBA:ARBA00004279}. Cytoplasm, cell cortex
CC {ECO:0000256|ARBA:ARBA00004544}. Early endosome
CC {ECO:0000256|ARBA:ARBA00004412}. Endosome
CC {ECO:0000256|ARBA:ARBA00004177}. Perikaryon
CC {ECO:0000256|ARBA:ARBA00004484}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR AlphaFoldDB; H0YV82; -.
DR STRING; 59729.ENSTGUP00000022046; -.
DR Ensembl; ENSTGUT00000002223.2; ENSTGUP00000002203.2; ENSTGUG00000002110.2.
DR GeneTree; ENSGT00940000157411; -.
DR HOGENOM; CLU_000192_7_7_1; -.
DR TreeFam; TF312960; -.
DR Proteomes; UP000007754; Chromosome 27.
DR GO; GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
DR GO; GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.
DR GO; GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0043204; C:perikaryon; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd01378; MYSc_Myo1; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR010926; Myosin_TH1.
DR InterPro; IPR036072; MYSc_Myo1.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF417; UNCONVENTIONAL MYOSIN-ID; 1.
DR Pfam; PF00612; IQ; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF06017; Myosin_TH1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 2.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 2.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51757; TH1; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 1..675
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 792..985
FT /note="TH1"
FT /evidence="ECO:0000259|PROSITE:PS51757"
FT REGION 552..574
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT BINDING 82..89
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 986 AA; 113766 MW; 35A55DDEA4FEAD4D CRC64;
MLRTVRRDHG AGFEKGRIYT FIGEVVVSMN PYKNLNIYGR DTIEQYKGRE LYERPPHLFA
IADAAYKAMK RRSKDTCIVI SGESGAGKTE ASKYIMQYIA AITNPGQRAE VERVKNILLK
SNCVLEAFGN AKTNRNDNSS RFGKYMDINF DFKGDPIGGH INNYLLEKSR VIVQQPGERS
FHSFYQLLQG GSEQLLRSLH LQKDASAYSY ICPGAQLKCS INDGAEFKAV ADAMKVIGFK
QEEIQTVYKI LAAILHLGNL KFYVDGDTPI IENSKVVSVI ADLLSTKAEL VEKALLFRTV
ATGRDVIDKQ HTEQEATYGR DAFAKAIYER LFCWIVTHIN DVIEVKNYDT TVHGKNTVIG
VLDIYGFEIF DNNSFEQFCI NYCNEKLQQL FIQLVLKQEQ EEYQREGIPW KHIDYFNNQV
IVDLVEQQHK GIIAILDDAC MNVGKVTDEM FLEALNNKLG KHAHFSSRKL CATDKTLEFD
RDFRIKHYAG DVIYSVTGFI DKNKDTLFQD FKRLMYNSSN PVLKMMWPEG KLSITEVTKR
PLTAATLFKN SMIALVDNLT LKEPYYVRCI KPNDKKSPQL FDEERCRHQV EYLGLLENVR
VRRAGFAYRQ TYEKFLHRYK MISEFTWPNH DLPSDKEAVR KLIECHGFQH DVAYGKTKLF
IRTPRTLFTL EELHAKMLVR IVLFLQKVWR GTLARLRYRR TRAALSIVRH YRRHKVRSYL
REVLRRFRDV RLLPDRGRGV PWPAPPKVLL RFQEALQDIF HRWRAAELIR SVPPEALPQL
RAKVAAMELL KGHRADIGLQ RAWQGNYIAL KPDSPQSSGS FTPVANELKR KDKYMNILFS
CHVRKVNRFN KVEDRAIFIT DRHLYKMDPM KQYKVMKTIP LYNLVGLSVS NGKDQLVVFH
TKDNKDLIVC LFSNDPSNDS RIGELVGVLA SHFKREKRTL HVAVTNPVQC SLHGRKCTVS
VETKINQPQP DFTKHRSGFV LCVPGN
//
