ID H0YVG3_TAEGU Unreviewed; 191 AA.
AC H0YVG3;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=COMM domain-containing protein 1 {ECO:0000256|ARBA:ARBA00016551};
GN Name=COMMD1 {ECO:0000313|Ensembl:ENSTGUP00000002284.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000002284.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000002284.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000002284.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_012427643.1; XM_012572189.1.
DR AlphaFoldDB; H0YVG3; -.
DR STRING; 59729.ENSTGUP00000002284; -.
DR Ensembl; ENSTGUT00000002304.2; ENSTGUP00000002284.2; ENSTGUG00000002215.2.
DR GeneID; 100220403; -.
DR KEGG; tgu:100220403; -.
DR CTD; 150684; -.
DR GeneTree; ENSGT00390000012029; -.
DR HOGENOM; CLU_126878_0_0_1; -.
DR InParanoid; H0YVG3; -.
DR OMA; WRIDGKS; -.
DR OrthoDB; 6795at2759; -.
DR TreeFam; TF332823; -.
DR Proteomes; UP000007754; Chromosome 3.
DR GO; GO:0031462; C:Cul2-RING ubiquitin ligase complex; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005769; C:early endosome; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0055037; C:recycling endosome; IEA:Ensembl.
DR GO; GO:0005507; F:copper ion binding; IEA:Ensembl.
DR GO; GO:0070300; F:phosphatidic acid binding; IEA:Ensembl.
DR GO; GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IEA:Ensembl.
DR GO; GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IEA:Ensembl.
DR GO; GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IEA:Ensembl.
DR GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IEA:Ensembl.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR GO; GO:0019871; F:sodium channel inhibitor activity; IEA:Ensembl.
DR GO; GO:0055070; P:copper ion homeostasis; IEA:Ensembl.
DR GO; GO:0006893; P:Golgi to plasma membrane transport; IEA:Ensembl.
DR GO; GO:2000009; P:negative regulation of protein localization to cell surface; IEA:Ensembl.
DR GO; GO:1902306; P:negative regulation of sodium ion transmembrane transport; IEA:Ensembl.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:Ensembl.
DR GO; GO:0048227; P:plasma membrane to endosome transport; IEA:Ensembl.
DR GO; GO:0031398; P:positive regulation of protein ubiquitination; IEA:Ensembl.
DR GO; GO:0032434; P:regulation of proteasomal ubiquitin-dependent protein catabolic process; IEA:Ensembl.
DR CDD; cd04749; Commd1_MURR1; 1.
DR InterPro; IPR017920; COMM.
DR InterPro; IPR033776; COMMD1_N.
DR InterPro; IPR037351; Murr1.
DR PANTHER; PTHR21199; COMM DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR21199:SF1; COMM DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF07258; COMM_domain; 1.
DR Pfam; PF17221; COMMD1_N; 1.
DR PROSITE; PS51269; COMM; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754}.
FT DOMAIN 120..188
FT /note="COMM"
FT /evidence="ECO:0000259|PROSITE:PS51269"
FT COILED 163..190
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 191 AA; 21171 MW; 4A3F89FEE9F9D1BA CRC64;
MAAPEPPPEG SRPLSALLGA IAQAAFQGSA GVPEELLRAQ LYPEAPPEEF RALRAKMGGL
LQSIASADMD LNQLEAFLTA QTKKQGGITS DQAAVIAKFW KNHRTQIHES LISQSRWDNV
LKNMNWRVDL KSQLRYIDQI NTPVAIVEME LGKNGQESEF LCLEFDEAKL SQMLKKLSEI
EESMTSLTQT T
//
