ID H0YYS4_TAEGU Unreviewed; 699 AA.
AC H0YYS4;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=NFKB repressing factor {ECO:0000313|Ensembl:ENSTGUP00000003453.2};
GN Name=NKRF {ECO:0000313|Ensembl:ENSTGUP00000003453.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000003453.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000003453.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000003453.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H0YYS4; -.
DR Ensembl; ENSTGUT00000003487.2; ENSTGUP00000003453.2; ENSTGUG00000003356.2.
DR GeneTree; ENSGT00940000157256; -.
DR HOGENOM; CLU_025268_0_0_1; -.
DR OMA; SVLWTNH; -.
DR TreeFam; TF326321; -.
DR Proteomes; UP000007754; Chromosome 4A.
DR GO; GO:0003676; F:nucleic acid binding; IEA:UniProtKB-UniRule.
DR CDD; cd02640; R3H_NRF; 1.
DR Gene3D; 3.30.160.20; -; 2.
DR Gene3D; 3.30.1370.50; R3H-like domain; 1.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR001374; R3H_dom.
DR InterPro; IPR036867; R3H_dom_sf.
DR InterPro; IPR034071; R3H_NRF.
DR PANTHER; PTHR14195; G PATCH DOMAIN CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR14195:SF5; PROTEIN, PUTATIVE-RELATED; 1.
DR Pfam; PF00035; dsrm; 2.
DR Pfam; PF01585; G-patch; 1.
DR Pfam; PF01424; R3H; 1.
DR SMART; SM00358; DSRM; 3.
DR SMART; SM00443; G_patch; 1.
DR SMART; SM00393; R3H; 1.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR SUPFAM; SSF82708; R3H domain; 1.
DR PROSITE; PS50174; G_PATCH; 1.
DR PROSITE; PS51061; R3H; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007754}.
FT DOMAIN 560..605
FT /note="G-patch"
FT /evidence="ECO:0000259|PROSITE:PS50174"
FT DOMAIN 609..673
FT /note="R3H"
FT /evidence="ECO:0000259|PROSITE:PS51061"
FT REGION 24..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..47
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 699 AA; 78110 MW; ED565D1D6C0B349C CRC64;
MEKVLKMAEG IDIGETRSYE LVPGRKLKRY RSPSDSPEPE EVPEPPKKVV PKFLPRVRPR
FEPIHFVTSA EKDGKKDNSL DNQRQEVNQE ANTNSMAQPA ENCTNSFVNA REVNPQLSSS
AGLGFAGPAA AAKKAVNSVD STTSNAVQVS VSPSTAPSAS ETFPPSAIML KQSFMEKLSA
AVWKNLTNPD ANTGTDKINF TYLLTRSIQA CKTNPEYIYV PLKEIAPADL PKSKKLLTDG
FACEVRCQNV YLATGYAGSK NGSRDRAAEQ AVKLLKKSVE VRVVQRKFKH TYHEDLVVCE
AGVCRPDFPP ALKPHEEFVV ANRDCVPMQP GTESMKGSAN ANKDWTSFVL TENASDAIGI
LNNSASYNKM SVEYKYELMP NRSWRCQVYL QDHCLAEGFG TKKTSKHAAA EEALKILQKM
QSNIASIKVT QVQKVGCSSR GSGRKKDLKD LVIYENSSNP VCTLNDTAQF NKMTVEYVFE
RMTGMRWKCK VMLEDEFIAE AVGVKKSVKH EAAEEAVKIL KKTQPTVVNN LKKGTVEDVI
SRNEIRGRSA EEAFKQKIKE DNIGNQILRK MGWTGGGLGK DGEGIREPIS VKEQFKREGL
GLDVERVNRI AKRDIEEIIR NYARSDSHID LTFSRELTMD ERKQIHQIAQ KYGLKSKSHG
QGHNRYLVVS RKRRKEDLLD QLKQEGQVGH YELIMPQAN
//
