ID H0YYU7_TAEGU Unreviewed; 299 AA.
AC H0YYU7;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=Interleukin-1 {ECO:0000256|RuleBase:RU003753};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000003479.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000003479.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000003479.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Lysosome
CC {ECO:0000256|ARBA:ARBA00004371}. Secreted, extracellular exosome
CC {ECO:0000256|ARBA:ARBA00004550}.
CC -!- SIMILARITY: Belongs to the IL-1 family. {ECO:0000256|ARBA:ARBA00010448,
CC ECO:0000256|RuleBase:RU003753}.
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DR AlphaFoldDB; H0YYU7; -.
DR STRING; 59729.ENSTGUP00000003479; -.
DR Ensembl; ENSTGUT00000003515.2; ENSTGUP00000003479.2; ENSTGUG00000003368.2.
DR GeneTree; ENSGT00950000182943; -.
DR HOGENOM; CLU_083639_0_0_1; -.
DR InParanoid; H0YYU7; -.
DR OMA; QKCLVMS; -.
DR TreeFam; TF300203; -.
DR Proteomes; UP000007754; Chromosome 22.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005149; F:interleukin-1 receptor binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR Gene3D; 2.80.10.50; -; 1.
DR InterPro; IPR000975; IL-1_fam.
DR InterPro; IPR008996; IL1/FGF.
DR PANTHER; PTHR10078:SF30; INTERLEUKIN-1 BETA; 1.
DR PANTHER; PTHR10078; INTERLEUKIN-1 FAMILY MEMBER; 1.
DR Pfam; PF00340; IL1; 1.
DR PRINTS; PR00264; INTERLEUKIN1.
DR SMART; SM00125; IL1; 1.
DR SUPFAM; SSF50353; Cytokine; 1.
PE 3: Inferred from homology;
KW Lysosome {ECO:0000256|ARBA:ARBA00023228};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW Secreted {ECO:0000256|RuleBase:RU003753}.
SQ SEQUENCE 299 AA; 33410 MW; 175B47DB5DC61573 CRC64;
MLWWWDWWGP GHMEARLSSY IPFLPQKPRL DLEGTSPGVG IQVTVTKGPL SRTFRQAAVL
VVAVTKLLKQ PSRKDFADSD LGSFLDDIFG MRGCQGWHPS QRIFLGDILG PRSSILLTVS
LPTEPVSFRC IRGSYTRAPV FRYTRSQSFD ILDIDHKCFV LESPTQLVAL HLQGPSAGQK
VKLNIALYRP RPSQGSPGSG RMPVALGIKG YQLYMSCVMS GTKPVLQLEE ADIRRDIESV
ELTRFIFYRL DSPSEGTTRF ESAAFPGWFV CTSLQPRQPV GITNTPDQVN IATYELSGR
//
