ID H0Z0H5_TAEGU Unreviewed; 1210 AA.
AC H0Z0H5;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 70.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN Name=MOV10L1 {ECO:0000313|Ensembl:ENSTGUP00000004062.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000004062.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000004062.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000004062.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- SIMILARITY: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
CC {ECO:0000256|ARBA:ARBA00005601}.
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DR AlphaFoldDB; H0Z0H5; -.
DR STRING; 59729.ENSTGUP00000004062; -.
DR Ensembl; ENSTGUT00000004107.2; ENSTGUP00000004062.2; ENSTGUG00000003947.2.
DR GeneTree; ENSGT00940000160150; -.
DR HOGENOM; CLU_001666_6_4_1; -.
DR InParanoid; H0Z0H5; -.
DR OMA; YDRERAH; -.
DR TreeFam; TF323999; -.
DR Proteomes; UP000007754; Chromosome 1A.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR GO; GO:0007281; P:germ cell development; IEA:Ensembl.
DR GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProtKB-KW.
DR GO; GO:0007283; P:spermatogenesis; IEA:Ensembl.
DR CDD; cd18078; DEXXQc_Mov10L1; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR049080; MOV-10-like_beta-barrel.
DR InterPro; IPR049079; Mov-10_helical.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF322; RNA HELICASE MOV10L1; 1.
DR Pfam; PF13086; AAA_11; 2.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF21634; MOV-10_beta-barrel; 1.
DR Pfam; PF21635; Mov-10_helical; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754}.
FT DOMAIN 751..941
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 1210 AA; 135769 MW; 4DF10FDEB5956142 CRC64;
MLALLSKALS YVWRRADDED ERWETSGDKE LKRVQGVVTR LCHDYGMIDD MIVFTKDVVT
KNMLLAVGQE VIATVEEDKT SGGLKAVRVD TIQNTQEDFS PTCDATELNK KTLIGSITSL
SVDGGYINQN TYFAMQDVWE DFKPYEGDWV QAKYYINSAT WKTEAVAVRP LRYKQVNKVR
ISNICGRTGT VDDNIFFTLD SLRLPDGYLP RRHDLVNTIV VESSQSCYIW RALCLVPVSQ
DGQSHSNEGN VDEPYEDIMR DRGELKVSRM TDFGTLKQGE SKRMIVWIEN KGSVPQSLIS
CRLAGWVKDK QFSVEIPQNC ENSPSFPIRQ ENLSKAAVNS FSNSGGSTCE SLDHTSIMKN
GVIPEGINFQ DTNLSRTKEN NSVVKAENMQ NGESEQKDHV EQTAKHSNIT PEIVIPPGEK
IFIVVICTAV IHGHSKELLL LGFSDFTVGR YIEATVTNEE ELLIAPVQPY SPRKTEIITD
SQPRKTTVVA PKHKRNKRRW CSNFLPHYTI PDELRKCVER HLDILTFQPL LAERLNLNNY
KANFSTLLWL EEIQAEMDLK DYYMSGVTLK RNGNLLVLEV PGVEEGRPRL VPGDKVILKS
QVYSDHIIEY IAHVAEICEE DVTLKVNADF ECAYNLEPMD VEFVHCSIPS RRCQLAIQQA
VYLGEKVLFP ERLVLQSPQA IKTQNTTEYC AVDDGLKQAS QQENKVKKRQ NKQTKVDETV
ALKQRDGEFF NPVLNVQQKL AVKRILSGEC RPTPYLLFGP PGTGKTVTVI EAILQIHFTL
PDSRILVCAP SNAATDLICL RLHQSSLLKP GTMVRVNAAF RSAEQIDDMV KPYCKDGDDI
QKALWSRIVI TTCSSAGLFY QIDTRLGHFT HVILDEAGQA SEPESLIPIG LISEADGQII
LVGDPKQLGP VIKSKLAESF GLSMSLLERL SSRELYMRDE DAFGACGAYN PLLITKLTKN
YRSHSALLAL PSKLFYHKEL EVCADTSVVT SFLNWEKLPR KGFPLIFHGI RGTETREGHS
PSWFNPAEAV QVMKYCCQLT GSEYSAVPVA DIGVIAPYRK QVEKIRFLLR SIDLEDIKVG
TVEEFQGQEY MVIILSTVRS QKVVIDDEKH SLGFLCNPKR FNVAITRAKA LLIVVGNPHI
LVKDPCFCAL LEYSLMNGVY IGCDLPAELE RLQKLPTSAT SPAACAERAG AAMVRASQVQ
HVLYCHFAGR
//
