ID H0Z317_TAEGU Unreviewed; 694 AA.
AC H0Z317;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=DDHD domain containing 2 {ECO:0000313|Ensembl:ENSTGUP00000004959.2};
GN Name=DDHD2 {ECO:0000313|Ensembl:ENSTGUP00000004959.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000004959.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000004959.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000004959.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H0Z317; -.
DR STRING; 59729.ENSTGUP00000004959; -.
DR Ensembl; ENSTGUT00000005008.2; ENSTGUP00000004959.2; ENSTGUG00000004804.2.
DR GeneTree; ENSGT00940000156808; -.
DR HOGENOM; CLU_006932_0_0_1; -.
DR InParanoid; H0Z317; -.
DR OMA; DGRNCQY; -.
DR OrthoDB; 1365902at2759; -.
DR TreeFam; TF314133; -.
DR Proteomes; UP000007754; Chromosome 22.
DR GO; GO:0034451; C:centriolar satellite; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0016020; C:membrane; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0004806; F:triglyceride lipase activity; IEA:Ensembl.
DR GO; GO:0034389; P:lipid droplet organization; IEA:Ensembl.
DR GO; GO:0007626; P:locomotory behavior; IEA:Ensembl.
DR GO; GO:0000266; P:mitochondrial fission; IEA:Ensembl.
DR GO; GO:0090141; P:positive regulation of mitochondrial fission; IEA:Ensembl.
DR GO; GO:0019433; P:triglyceride catabolic process; IEA:Ensembl.
DR GO; GO:0008542; P:visual learning; IEA:Ensembl.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR004177; DDHD_dom.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR004170; WWE-dom.
DR PANTHER; PTHR23509; PA-PL1 PHOSPHOLIPASE FAMILY; 1.
DR PANTHER; PTHR23509:SF7; PHOSPHOLIPASE DDHD2; 1.
DR Pfam; PF02862; DDHD; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF02825; WWE; 1.
DR SMART; SM01127; DDHD; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS51043; DDHD; 1.
DR PROSITE; PS50918; WWE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007754}.
FT DOMAIN 12..95
FT /note="WWE"
FT /evidence="ECO:0000259|PROSITE:PS50918"
FT DOMAIN 474..680
FT /note="DDHD"
FT /evidence="ECO:0000259|PROSITE:PS51043"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 429..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 588..631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 429..450
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 598..617
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 694 AA; 78873 MW; 1BAF4849E13892FE CRC64;
MEPPRPPPAE PAEPEPGGRY EPVAPHWFYR RLNEPRERWV PFSAQDSRRL EEAHGAGKEQ
DDVVVPTSGG RYDVHLRARR RVAVYWEEEA AEVRRCTWFY KGDKDNKFIP YSESFSEELE
EAYMIAVTLG EWKKKLESPN REVIVLHNPK LMVHYHPVAS SDDWVSTPTE QGRPRTVKRG
VDNIAVEIPS GEPLQIDHLV FVVHGIGPAC DIRFRSIVQC VNDFRTVSLS MLQAHFRKAQ
EQQQVGRVEF LPVNWHSSLH STGVDVDLER ITLPSINRLR HFINDTILDV FFYNSPTYCQ
TIVDTVASEM NRLHRLFLQR NPHFRGGVSI AGHSLGSLIL FDLLTNQKAD PEEDERCAQG
SRTTSGTGGI EEVKEILKKL ELSEYCDVFE KEKMDRQAVF LCTEKNLKEM GIPLGPRMKI
LHYISSETEM KDRSSAAPGH DEREAEPGDS SEGVRSCQYR DVGLGQVSAN YPQLNYKPTI
FFAFGSPIGM FLTVRGVKRI DPNYSLPTCK GFFNIFHPFD PVAYRIEPMI VPELEFEPML
LPHHKGRKRM HLELKEGLTR MSVDLKNNLL GSLRVAWQSF TRAPVPALEA GSSEAEADSE
ASTEKQPDTK PEEPPAAVKE ETPPISPINV GRLNGGNRID YVLQEKPIES FNEYLFALQG
HLCYWESEDT VLLVLKEIYQ TQGITLDQPL PGSQ
//
