ID H0Z3W9_TAEGU Unreviewed; 581 AA.
AC H0Z3W9;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=APOBEC1 complementation factor {ECO:0000313|Ensembl:ENSTGUP00000005263.2};
GN Name=A1CF {ECO:0000313|Ensembl:ENSTGUP00000005263.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000005263.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000005263.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000005263.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR RefSeq; XP_002187149.2; XM_002187113.2.
DR AlphaFoldDB; H0Z3W9; -.
DR STRING; 59729.ENSTGUP00000005263; -.
DR Ensembl; ENSTGUT00000005315.2; ENSTGUP00000005263.2; ENSTGUG00000005090.2.
DR GeneID; 100231854; -.
DR KEGG; tgu:100231854; -.
DR CTD; 29974; -.
DR GeneTree; ENSGT00940000158678; -.
DR HOGENOM; CLU_022960_5_1_1; -.
DR InParanoid; H0Z3W9; -.
DR OMA; YATYEVY; -.
DR OrthoDB; 3184171at2759; -.
DR TreeFam; TF314932; -.
DR Proteomes; UP000007754; Chromosome 6.
DR GO; GO:0030895; C:apolipoprotein B mRNA editing enzyme complex; IEA:Ensembl.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0140767; F:enzyme-substrate adaptor activity; IEA:Ensembl.
DR GO; GO:0003727; F:single-stranded RNA binding; IEA:Ensembl.
DR GO; GO:0016554; P:cytidine to uridine editing; IEA:Ensembl.
DR GO; GO:0010609; P:mRNA localization resulting in post-transcriptional regulation of gene expression; IEA:Ensembl.
DR GO; GO:0016556; P:mRNA modification; IEA:Ensembl.
DR GO; GO:2000623; P:negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:Ensembl.
DR GO; GO:0050821; P:protein stabilization; IEA:Ensembl.
DR CDD; cd19900; DSRM_A1CF; 1.
DR CDD; cd12486; RRM1_ACF; 1.
DR CDD; cd12490; RRM2_ACF; 1.
DR CDD; cd12498; RRM3_ACF; 1.
DR Gene3D; 3.30.160.20; -; 1.
DR Gene3D; 3.30.70.330; -; 3.
DR InterPro; IPR044461; A1CF_DSRM.
DR InterPro; IPR034538; ACF_RRM1.
DR InterPro; IPR006535; HnRNP_R/Q_splicing_fac.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR NCBIfam; TIGR01648; hnRNP-R-Q; 1.
DR PANTHER; PTHR21245:SF8; APOBEC1 COMPLEMENTATION FACTOR; 1.
DR PANTHER; PTHR21245; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; 1.
DR Pfam; PF14709; DND1_DSRM; 1.
DR Pfam; PF00076; RRM_1; 3.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR PROSITE; PS50102; RRM; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176}.
FT DOMAIN 56..134
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 136..218
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 231..303
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 34..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 581 AA; 63872 MW; 3E8270C208C9F0EA CRC64;
MESNHKSGDG LTGTQKEAAL RALIQRTGYN LIQENGQRKY GGPPPGWDGP PPERGCEIFI
GKLPRDLFED ELIPLCEKIG KIYEMRMMMD FNGNNRGYAF VTFSNKQEAK NAIKTLNNYE
IRNGRLLGVC ASVDNCRLFV GGIPKTKKRE EILAEMKKVT DGVVDVIVYP SAADKTKNRG
FAFVEYESHR AAAMARRKLL PGRIQLWGHP IAVDWAEPEV EVDEDTMSSV KILYVRNLML
STTEETIEKE FNSIKPGAVE RVKKIRDYAF VHFNKREHAV EAMKALNGKV LDGSPIEVTL
AKPVDKDSYV RYTRGTGGRA PVLQGDYTYT LGHLYDPTAA YLGAPVFYAP QAYAAIPNLH
FPAAKGLGSR SILRPPSVRG AAGVRGLGGR GYLAFPGLGR GYHLKGDKRG EEKLYDLLPG
MELTPMNHVT LKPQGIKLAP QILEEICQKN NWGQPVYQLH SAIGQDQRQL FLYKITIPAL
ASQNPTIHPF TPPKLSAYID EAKTYAAEYT LQTLGIPVEG AEVPPAAPAF PGYTIANAAA
AVTATQLKQA VTLGQDLATY ATYEAYPAFA VAARSDGYGA F
//
