ID H0Z514_TAEGU Unreviewed; 1124 AA.
AC H0Z514;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Zinc finger MYND-type containing 8 {ECO:0000313|Ensembl:ENSTGUP00000005660.2};
GN Name=ZMYND8 {ECO:0000313|Ensembl:ENSTGUP00000005660.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000005660.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000005660.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000005660.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H0Z514; -.
DR STRING; 59729.ENSTGUP00000022218; -.
DR Ensembl; ENSTGUT00000005718.2; ENSTGUP00000005660.2; ENSTGUG00000005447.2.
DR GeneTree; ENSGT00940000154897; -.
DR HOGENOM; CLU_008433_0_0_1; -.
DR TreeFam; TF317221; -.
DR Proteomes; UP000007754; Chromosome 20.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd05508; Bromo_RACK7; 1.
DR CDD; cd20160; PWWP_PRKCBP1; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR021931; ZMYND8.
DR InterPro; IPR037967; ZMYND8_Bromo_dom.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR46453; PROTEIN KINASE C-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR46453:SF3; PROTEIN KINASE C-BINDING PROTEIN 1; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF12064; DUF3544; 1.
DR Pfam; PF00855; PWWP; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS50812; PWWP; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 112..182
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 224..274
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT DOMAIN 971..1005
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT REGION 1..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 359..461
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 530..808
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1016..1064
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 918..967
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..36
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..58
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 359..391
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 406..461
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 548..646
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 659..684
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 685..738
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 757..808
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1016..1046
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1124 AA; 124782 MW; 2722E8B244F33C94 CRC64;
MHPQSLAEEE IKAEQEVVEG MDISTRSKDP GSAERTAQKR KFPSPPHSSN GHSPQDASTS
PIKKKKKPGL LNSNNKEQKI TVAECIETQS KAMTMLTIEQ LSYLLKFALQ KMKQPGTEPF
QKPVSLDQHP DYAEYIFHPM DLCTLEKNVK KKMYGCTEAF LADAKWILHN CIIYNGGNHK
LTQTAKVIIK ICEHEMNEIE VCPECYLAAC QKRENWFCEP CSNPHPLVWA KLKGFPFWPA
KALRDKDGQV DARFFGQHDR AWVPINNCYL MSKEIPFSVK KTKSIFNSAM QEMEVYVDNI
RRKFGVFNYA PFRTPYTPNN QYQMLLDPAN PAAGTAKTDK QEKIKLNFDM TASPKILMSK
SMLSSSTGRR ISLTDMPRSP MSTNSSVHTG SDVEQDAEKK ATSSHFSASE ESMDFIEKNT
ASPAPTRTGQ AGSLSGSPKP FSPQASTPIS AKQERTSTPG SILNLNLDRS KAEMDLKELS
ESVQQQSTPV QLISPKRQIR SRFQLNLDKT IESCKAQLGI NEISEAVYTA VEHSDSEDSE
KSDTSDSEYS DEDQKSKNDQ EDGEDKEGAR SDKESLSLKK KPKLPAQNED KEELKSTSPE
VEKTEEPVKE KAVSDTEKEF SEKGKSLQHP AKEKLKGKDE TDSPTVHLGL DSDSESELVI
DLGDDHCTRE GRKNKKDSKE SSPKQDVVGK TPPSSSASNQ PLPETPVLTR SASQTPPAGV
TATTSAASTV SAPSAATGSP VKKQRPLLPK ETAPAVQRVV WNSSNKFQTS SQKWHMQKVQ
RQQQQQQSQQ SQSQQPQSSQ GTRYQTRQAV KAVQQKEITQ STSTSTITLV TSTQPISMVT
SSGSAGTLSS SLNTDLPIAT ASADVAADIA KYTSKMMDAI KGTMTEIYND LSKNTTGSTI
AEIRRLRIEI EKLQWLHQQE LSEMKHNLEL TMAEMRQSLE QERDRLIAEV KKQLELEKQQ
AVDETKKKQW CANCKKEAIF YCCWNTSYCD YPCQQAHWPE HMKSCTQSAT ATQQETDTEI
STETLNKSSQ PSSSVQSTTT ETASTPKEKE GSADKSKENV TIATGVTSNQ PIKLVQVPQT
TTYIPTTQPT ITIPVVVSPS AGTVAMRTGV QYVQTTMPVQ VRRV
//
