ID H0Z621_TAEGU Unreviewed; 1334 AA.
AC H0Z621;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Formin homology 2 domain containing 1 {ECO:0000313|Ensembl:ENSTGUP00000006019.2};
GN Name=FHOD1 {ECO:0000313|Ensembl:ENSTGUP00000006019.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000006019.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000006019.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000006019.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 59729.ENSTGUP00000020968; -.
DR Ensembl; ENSTGUT00000006078.2; ENSTGUP00000006019.2; ENSTGUG00000005820.2.
DR GeneTree; ENSGT00940000160212; -.
DR HOGENOM; CLU_000814_0_0_1; -.
DR TreeFam; TF316268; -.
DR Proteomes; UP000007754; Chromosome 11.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR041387; FHOD1_GBD_N.
DR InterPro; IPR014768; GBD/FH3_dom.
DR PANTHER; PTHR45920:SF2; FH1_FH2 DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR45920; FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I; 1.
DR Pfam; PF02181; FH2; 1.
DR Pfam; PF18382; Formin_GBD_N; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51444; FH2; 1.
DR PROSITE; PS51232; GBD_FH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007754}.
FT DOMAIN 125..516
FT /note="GBD/FH3"
FT /evidence="ECO:0000259|PROSITE:PS51232"
FT DOMAIN 799..1193
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT REGION 1..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 397..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 588..634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 784..805
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1236..1316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..423
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 441..463
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1240..1266
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1334 AA; 146254 MW; ADA59B69171369E9 CRC64;
MPERSSGAPQ SLKHPGAWSI LPGRARGRAQ RAASGSPGPG RARGPGPARA RPGSGVARGR
GGGGAMAVAE AAEATVPCRV QYLEDADPFA FGSFPEPRRA PVYALEEAAG PGAQLPALHR
LVGAPLPLED CTLQVSPSGH YLDLDLSLLE QKDDLEGFYE EVRKGRRPTL ILRTQLSVRV
HAIIEKLYNS QGPELRRSLF SLKQLFQEDK DLVPEFVNLE GLTCLIKVGA EADQNYQNYI
LRALSQIMLF VDGMQGVINH NETVQWLYTL SGSPFRLVVK TALKLLLVFV EYTEPNALLL
IRAVNAVDQA RGACPWSNLM AILEQRNGAD TELLVFTMTL INKTLAALPD QDTFYDVTDC
LEQQGMEQVV QQYLGSKGTD LDLKQQFTLY ESALKLEDDV EEPPSGGRKE RRRTDEGRRG
RRSQGGSQDP SADAQPLLES PGTPKEPPAE DTLPIPAPSS PAEPCPTSIY NSTSSVRLAL
APPLAEKEQP PGPGERSVYK ARFLENLAAA QKEKISSMAK GRLDVLSDTT LEHPTALAWE
RDHGTSDSGM EPPSIRSHLA RSDITDSCST ISSDTKFMLD MLYAKGSSES GREKTFHERP
LSPQIQGEVE MDAKGSSSQE QESPRLRGRA PDGPVASAHA KLVRAMSSID DETHTQKLEN
TGMMPIKKDT ELTWERLETI PVQLKIKDLD FTDLGEEEDF DILDTGPMTN GSFLHPGIEA
MSAGTFMAPP PPPALPGCPP PPPPPPAIPG CPPPPPPALP GCPPPPPPEL PGCPLPPPPP
PAVPGCLPPP GLPGPSTTDG PSQAKKKRTV KLFWKELKQL DGTVEPGRFG QGTLWASLQN
VEVNTAKLEH LFESRSKEAP TSKKAIDGKK VVVVLDPKRS NAINIGLTVL PPIHIIKTAV
LNFDEFAVSK EGIEKILTMV PTEEEKQKIQ EAQLANPDVP LGSAEQFLLS LSSISDLTAR
LQLWAFKLDY ESLEQEIAEP LFDLKVGMEQ LARNHTFKCI LATLLATGNF LNGSQSRGFE
LSYLEKVSEV KDTVHRQSLL YHLCQMVVEK FPETTDLYSE IASITRSAKV DFEELANSLV
QLERRCRASW HNLKVIAKHE TKPVLKTKLT EFLKDSTQRI IVLKVVHRRV LNRFHSFLLY
LGYPASVARE VKVTSICKLL QEFALEYRTC RERVLLQQKK RAAHRERSKT RGRLITETEK
FSGIAEAVLP PAMVSSSPKE QMEAGHESMK ILLTSPTDLP ARRSRASQGT GHGTPTQTSP
AQEDVPSSPD DASDEIMDQL VKSVTHNPNP RPCPNKERRR SRVNRKSLRR TLKSGLSDDL
VQALGLGQAP GMEV
//
