ID H0Z811_TAEGU Unreviewed; 1375 AA.
AC H0Z811;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=Secretory phospholipase A2 receptor {ECO:0000256|ARBA:ARBA00044135};
DE AltName: Full=180 kDa secretory phospholipase A2 receptor {ECO:0000256|ARBA:ARBA00044310};
DE AltName: Full=M-type receptor {ECO:0000256|ARBA:ARBA00044268};
GN Name=PLA2R1 {ECO:0000313|Ensembl:ENSTGUP00000006712.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000006712.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000006712.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000006712.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane
CC protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00479}.
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DR STRING; 59729.ENSTGUP00000021298; -.
DR Ensembl; ENSTGUT00000006778.2; ENSTGUP00000006712.2; ENSTGUG00000006488.2.
DR GeneTree; ENSGT01050000244842; -.
DR HOGENOM; CLU_002069_2_0_1; -.
DR TreeFam; TF316663; -.
DR Proteomes; UP000007754; Chromosome 7.
DR GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd00037; CLECT; 8.
DR CDD; cd00062; FN2; 1.
DR CDD; cd00161; RICIN; 1.
DR Gene3D; 2.80.10.50; -; 1.
DR Gene3D; 2.10.10.10; Fibronectin, type II, collagen-binding; 1.
DR Gene3D; 3.10.100.10; Mannose-Binding Protein A, subunit A; 8.
DR InterPro; IPR001304; C-type_lectin-like.
DR InterPro; IPR016186; C-type_lectin-like/link_sf.
DR InterPro; IPR016187; CTDL_fold.
DR InterPro; IPR000562; FN_type2_dom.
DR InterPro; IPR036943; FN_type2_sf.
DR InterPro; IPR013806; Kringle-like.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR PANTHER; PTHR22803; MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED; 1.
DR PANTHER; PTHR22803:SF74; SECRETORY PHOSPHOLIPASE A2 RECEPTOR; 1.
DR Pfam; PF00040; fn2; 1.
DR Pfam; PF00059; Lectin_C; 8.
DR PRINTS; PR00013; FNTYPEII.
DR SMART; SM00034; CLECT; 8.
DR SMART; SM00059; FN2; 1.
DR SMART; SM00458; RICIN; 1.
DR SUPFAM; SSF56436; C-type lectin-like; 8.
DR SUPFAM; SSF57440; Kringle-like; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR PROSITE; PS50041; C_TYPE_LECTIN_2; 8.
DR PROSITE; PS51092; FN2_2; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 140..186
FT /note="Fibronectin type-II"
FT /evidence="ECO:0000259|PROSITE:PS51092"
FT DOMAIN 204..320
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 348..465
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 488..600
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 643..763
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 785..904
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 932..1060
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1084..1188
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
FT DOMAIN 1220..1341
FT /note="C-type lectin"
FT /evidence="ECO:0000259|PROSITE:PS50041"
SQ SEQUENCE 1375 AA; 159532 MW; 7082B0B7F1A98405 CRC64;
MANGKGIFII QSENSSLCIK VDRASLVLED CGQLSEKMLW KWVSNHRLFN VGSSTCLGLN
ISRPEQPLTM LECDSTQYSL WWNCDGKALV GVSEFKLAVE NNKHIVARKK STCQWKQYMS
YDEDLCEHPF QETYTLLGNS FGFPCVFPFK YNNKWYYECT RDGKESEWCA TTTHYEQDEK
WGFCPNAESG CDIFWKKNPN THICYQFNFA SVLSWREARA ACQLQGGDLL SVTDPEEQNY
ISNLSRQLNS TDMMLWMGLN RLDEDAGWQW SDGAPLMFVN WRANVSDSRF KENHCAVINP
RLKYGWNSYL CESGLPFVCK KYLNETENET LDTWQYYATR CDAGWYPHNR NCYRLHKEEK
SWNDASLSCQ SENSRLISVS SMADEELLFN LLKSENVTET WIGLYSNSTP VVFEWSDSTP
VKFSNWHRQE PNTFQRTGQL CVSAQRPEGH WRIKKCEDKS FYICKKAGEF NSVSPELESN
CPEGWERHGG YCYKIDSTPR SFEHASSGYF CPSELVSVTN RFEQAFINSM IRSMAESERT
YFWIGLQDLN NTGEYFWLST AGKNLSVSYT NWNKYQPRHS GGCVAMRGEH PVGYWEVKSC
KNFRAMSLCK QKVNSYEEPE LTFQKYSSSC YFGWESEPNL LNCYKIFHNE KVLMRRTWDE
AEALCQDFGA HLASFSHIYE ETYLNNLLYT IFDRTEERQF WIGFNKRNAL SGGTWQWSDR
TPVVTSFLED KYLEDDSRNC GVFKVNRTVF PAHCTEKREW ICKIPKGVKP MSPVWYTAEL
PWSYYQGAEY LFHVSPAEWE TCKFVCGWLR GGLAIINSSG EETFIQNKIR KLSTSDVHWW
IGLHAENLSD EFRWLDESPV TYQNWDEGRE RDLQKPGKRC GFVSSQTGLW GDENCTVSLP
CICKRIIPKK IEKEIPKDPN QRGACPKGWL HFGFKCFLIQ IPKDPEHLRN WYSAQEFCSN
YDGSLAILED ELEQAFITMN LYGWKRSVWI GFQSDDYEKW LNENPQMYSN WSPVELVDRQ
HFNVQDQVPL CTLVSNNPNF YFTGKWYLEN CQKKYGFVCQ KTQDTSRHFI NASDMYPVPD
TLEYGNRMYK LISGNFTWSS ALQACMANSA ELVSITDQYH QAFLTIIVNR LGYSHWIGLF
TSDNGLNFEW SDGTRSLFTF WEDDESQAFG SCVYIDTSGH WKSANCEQLL QGAVCHVPSK
KKLNAYKGLC SEKTVPWIKF KNSCYSFSTV LQGMSFDTAY EVCKNQGSNL LTIQDEDENA
FILEELHSFG YSVQMVWLNI LLVTDNETVS WFDGSPLNYS NWGIREPEFN NLKGNFCISL
RTTDGVWQLS PCREKKGFVC KMDADTDTTE SSEKASSELP QQKAVTHLVM QLFPV
//
