ID H0ZAK3_TAEGU Unreviewed; 742 AA.
AC H0ZAK3;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=LON peptidase N-terminal domain and ring finger 1 {ECO:0000313|Ensembl:ENSTGUP00000007607.2};
GN Name=LONRF1 {ECO:0000313|Ensembl:ENSTGUP00000007607.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000007607.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000007607.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000007607.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H0ZAK3; -.
DR STRING; 59729.ENSTGUP00000007607; -.
DR Ensembl; ENSTGUT00000007685.2; ENSTGUP00000007607.2; ENSTGUG00000007379.2.
DR GeneTree; ENSGT00440000033329; -.
DR HOGENOM; CLU_013989_1_1_1; -.
DR InParanoid; H0ZAK3; -.
DR OMA; KYKKQGV; -.
DR TreeFam; TF327043; -.
DR Proteomes; UP000007754; Chromosome 4.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16514; RING-HC_LONFs_rpt2; 1.
DR Gene3D; 2.30.130.40; LON domain-like; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR003111; Lon_prtase_N.
DR InterPro; IPR046336; Lon_prtase_N_sf.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR027370; Znf-RING_euk.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR23327:SF4; LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 1; 1.
DR PANTHER; PTHR23327; RING FINGER PROTEIN 127; 1.
DR Pfam; PF02190; LON_substr_bdg; 1.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR Pfam; PF13445; zf-RING_UBOX; 1.
DR SMART; SM00464; LON; 1.
DR SMART; SM00184; RING; 2.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51787; LON_N; 1.
DR PROSITE; PS00518; ZF_RING_1; 2.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 449..487
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 535..735
FT /note="Lon N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51787"
FT REGION 1..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 742 AA; 83463 MW; 8A36C1CDDD8B5DFD CRC64;
GARPGVWSRR PGAGAPTPPS PQPRSRWQRP SPARHRGLGA AAGAGRSGAP ARGGRQSGSC
CWKRWARPWR RCASAPSAEP APSGPSWTCL VLNYRLRQGA VRGRERGAEG AALLRLPRFL
GEPVTVPCGH TYCRRCLRRE LRARCRRCRD WLLPAGGTST AAAPLRTSVV LNRLAEKWFP
GECERARAGT RLEELLTQGR FREALGAANQ ALRADSSDLM LRIYRAESYV GLQEYKTAIE
DLNFVISKMP NWPEVYFQKG KVLQDSGFVG DALQLFLQCL ALDEDFLPAK LEVEKILCDV
LSPEKLGESL KESAWNSPHI RNKPFILGSE VTASYCNLQL CPPQSLGGSD VLEPVSGGLN
RAQSAHALNS TKDLAKEDGL KRVSSEPLLS GQGKGALLKR KLSFSEQDTV VFEDGRNKHK
KQGESTKRDI TLAFGAIPGD LIDVSDFECS LCMRLFFEPV TTPCGHTFCK GCLERCLDHA
PQCPLCKESL KEYLASRKYS ITELLEELIM KYLSDELFER KRIHAEETAE HSNLTKNVPM
FVCTMAYPTV PCPLHVFEPR YRLMIRRSME TGTKQFGMCI SDSQNGFADY GCMLQIRNVH
FLPDGRSVVD TIGGKRFRVL RRGMKDGYCT ADIEYLEDVK VADEELKKLR ELHNFVYNQA
CSWFQNLRNK FRTQILQHFG PMPDREENIQ AMPNGPAWCW WLLAVLPVDP RYQLSVLSMM
SLKDRLIKIQ HILTYFSRDQ SK
//
