ID H0ZDV8_TAEGU Unreviewed; 309 AA.
AC H0ZDV8;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=LHFPL tetraspan subfamily member 4 {ECO:0000313|Ensembl:ENSTGUP00000008770.2};
GN Name=LHFPL4 {ECO:0000313|Ensembl:ENSTGUP00000008770.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000008770.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000008770.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000008770.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; H0ZDV8; -.
DR STRING; 59729.ENSTGUP00000008770; -.
DR Ensembl; ENSTGUT00000008863.2; ENSTGUP00000008770.2; ENSTGUG00000008520.2.
DR GeneTree; ENSGT00990000203541; -.
DR HOGENOM; CLU_084868_1_1_1; -.
DR InParanoid; H0ZDV8; -.
DR OMA; CAVRWAI; -.
DR TreeFam; TF321143; -.
DR Proteomes; UP000007754; Chromosome 12.
DR GO; GO:0098982; C:GABA-ergic synapse; IEA:Ensembl.
DR GO; GO:0060077; C:inhibitory synapse; IEA:Ensembl.
DR GO; GO:0045211; C:postsynaptic membrane; IEA:Ensembl.
DR GO; GO:0099572; C:postsynaptic specialization; IEA:Ensembl.
DR GO; GO:0050811; F:GABA receptor binding; IEA:Ensembl.
DR GO; GO:0097112; P:gamma-aminobutyric acid receptor clustering; IEA:Ensembl.
DR GO; GO:0099645; P:neurotransmitter receptor localization to postsynaptic specialization membrane; IEA:Ensembl.
DR GO; GO:1905702; P:regulation of inhibitory synapse assembly; IEA:Ensembl.
DR Gene3D; 1.20.140.150; -; 1.
DR InterPro; IPR019372; LHFPL.
DR PANTHER; PTHR12489:SF14; LHFPL TETRASPAN SUBFAMILY MEMBER 4 PROTEIN; 1.
DR PANTHER; PTHR12489; LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN; 1.
DR Pfam; PF10242; L_HMGIC_fpl; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 309 AA; 33662 MW; 090BCA70211C77BF CRC64;
MLPSQEASKL YHDNYVRNSR AIGVLWAIFT ICFAIINVVV FIQPYWVGDS VNTPKPGYFG
LFHYCVGSGL AGRELSCRGS FTDFSTIPSG AFQAAAFFVL LSMVLTLGCI TCFALFFFCN
TATVYKICAW MQLLAALCLV LGCMIFPDGW DAETIRDMCG EKTGKYSLGD CSVRWAYILA
IIGILNALIL SFLAFVLGNR QNDLLHEELK TESKDFVGTA VSLECHCPVP CPSVVSLGVT
VLGVCVTWDG MGWDGMGWDG TGQDRVGWDG GPWLCRQQGW GQWGKGGSRD RVAGMGIGIC
RAHASDTVQ
//
