ID H0ZFF3_TAEGU Unreviewed; 943 AA.
AC H0ZFF3;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=RNA binding motif protein 19 {ECO:0000313|Ensembl:ENSTGUP00000009315.2};
GN Name=RBM19 {ECO:0000313|Ensembl:ENSTGUP00000009315.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000009315.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000009315.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000009315.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; H0ZFF3; -.
DR STRING; 59729.ENSTGUP00000009315; -.
DR Ensembl; ENSTGUT00000009414.2; ENSTGUP00000009315.2; ENSTGUG00000009017.2.
DR GeneTree; ENSGT00840000129953; -.
DR HOGENOM; CLU_008479_1_0_1; -.
DR InParanoid; H0ZFF3; -.
DR OMA; EFRTKEQ; -.
DR OrthoDB; 5477987at2759; -.
DR TreeFam; TF105725; -.
DR Proteomes; UP000007754; Chromosome 15.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0005730; C:nucleolus; IEA:Ensembl.
DR GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0040019; P:positive regulation of embryonic development; IEA:Ensembl.
DR CDD; cd12564; RRM1_RBM19; 1.
DR CDD; cd12567; RRM3_RBM19; 1.
DR CDD; cd12569; RRM4_RBM19; 1.
DR CDD; cd12318; RRM5_RBM19_like; 1.
DR CDD; cd12571; RRM6_RBM19; 1.
DR Gene3D; 3.30.70.330; -; 6.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR034419; RBM19_RRM3.
DR InterPro; IPR034420; RBM19_RRM4.
DR InterPro; IPR034423; RBM19_RRM5.
DR InterPro; IPR034421; RBM19_RRM6.
DR InterPro; IPR034418; RMB19_RRM1.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR003954; RRM_dom_euk.
DR PANTHER; PTHR48039; RNA-BINDING MOTIF PROTEIN 14B; 1.
DR PANTHER; PTHR48039:SF5; RNA-BINDING PROTEIN 28; 1.
DR Pfam; PF00076; RRM_1; 6.
DR SMART; SM00360; RRM; 6.
DR SMART; SM00361; RRM_1; 2.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 5.
DR PROSITE; PS50102; RRM; 6.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 2..79
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 295..370
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 402..480
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 587..659
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 715..796
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 817..897
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 83..122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 151..296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 370..399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 484..507
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 667..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..192
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..221
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 232..250
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 251..277
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..292
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 672..687
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 694..712
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 943 AA; 105169 MW; B03ECED1CA02295E CRC64;
MSRLIVKNLP SGMKEERFRK LFAAFGTLTD CCLKYTKDGR FRKFGFIGYK SEDEAQAALN
HFNKSFIDTS RLTVELCKSF GDPTKPKAWS KHSQKAPASE KQTKEPLASA APAGTKKGKK
KKDAVDNLKE LKEDKTFQEF LVVHQKRSQV ATWANDTLAE EPKKGKSAAA DYLNFDSDES
EELSEGGDEP SEDEEEIKGK KEGKKAATSK DLSDMDYLKS KVVKDSSSLS STEEETETEE
EESETEEDSG IAETPPEKRG KPKAQQTEQK TPAGKKKKGS TLESQASPGE ASTAFTVKLR
GAPSSITEEK IREFFFPLKP VAIRMGKKAQ GKNSGYIFVD LKSEAEMQRA LKRKKEFLGG
RCVEVSRCRN TPKEPVPAKP EHQPWQRTLR DDEEEEDLSE SGRLFVRNLP FTSTEEDLEK
IFSKYGPLSE IHFPIDKLTK KPKGFAFITY MIPEHAVKAL AELDGQVFQG RMMHLLPSTI
RKEKIEDGDA EESSSYKKSK EAKDKANSAS SHNWNALFVG TNAVADAMAQ KYNAAKSQVL
DAESKDSVAV RVALGETELV QEIRRFLVEN GVSLDSFSQA AGERSKTVIL VKNLPAGTSA
LELEQLFGHH GGLGRVLLPE GGITAIVEFL EPTEAKQAFT RLAYSKFHSV PLYLEWAPMG
VFLSPAPQKK KAGVPGKEDE AGLVPGEATK DSEEAAAQEE EEEDEEEEEE NIPGCTLFIK
NLNFATTEDT LKETFSKVGA LKSCTISKKK DKAGTLLSMG FGFVEYKKPE SAQKALRQLQ
GCTVDGHKLE VKLSERAVRP AVKSTRKKQI AKKQKTSKIL VRNIPFQATV REIRELFSTF
GELKTVRLPK KMAGTGSHRG FGFVDFVTKQ DAKKAFQALC HSTHLYGRRL VLEWADTEET
LEALRRKTAQ HFHDSPKKKK RSEILNEIME HLEEEDNNKD EDI
//
