ID H0ZIG6_TAEGU Unreviewed; 734 AA.
AC H0ZIG6;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=LON peptidase N-terminal domain and ring finger 2 {ECO:0000313|Ensembl:ENSTGUP00000010383.2};
GN Name=LONRF2 {ECO:0000313|Ensembl:ENSTGUP00000010383.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000010383.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000010383.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000010383.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H0ZIG6; -.
DR STRING; 59729.ENSTGUP00000034734; -.
DR Ensembl; ENSTGUT00000010493.2; ENSTGUP00000010383.2; ENSTGUG00000010057.2.
DR GeneTree; ENSGT00440000033329; -.
DR HOGENOM; CLU_013989_1_2_1; -.
DR TreeFam; TF327043; -.
DR Proteomes; UP000007754; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd16514; RING-HC_LONFs_rpt2; 1.
DR Gene3D; 2.30.130.40; LON domain-like; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR003111; Lon_prtase_N.
DR InterPro; IPR046336; Lon_prtase_N_sf.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR23327:SF5; LON PEPTIDASE N-TERMINAL DOMAIN AND RING FINGER PROTEIN 2; 1.
DR PANTHER; PTHR23327; RING FINGER PROTEIN 127; 1.
DR Pfam; PF02190; LON_substr_bdg; 1.
DR Pfam; PF13923; zf-C3HC4_2; 1.
DR SMART; SM00464; LON; 1.
DR SMART; SM00184; RING; 2.
DR SMART; SM00028; TPR; 4.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51787; LON_N; 1.
DR PROSITE; PS50005; TPR; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT REPEAT 224..257
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 491..529
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 577..734
FT /note="Lon N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51787"
SQ SEQUENCE 734 AA; 81398 MW; EEA05FB40891A755 CRC64;
MELGPGPCAL PPAAGAGARA AAAGGPCAEM LQVAEEAFRG GNFELAAEIY GSELAGLPQP
ERGLCLRRAD ALARAGRMAE ALDAYGAAAR LARLRPEELR ELAESVALSI RDKELRLPPW
GSGAAGGGGA EGEGLGDPAC CRPPELFACP LCRRLLCEPV TLHCGHTHCR RCAEPGDCGR
CHRPRRPAEP SPAAAALPPA AGRPRVNVVL GNLLHKWFGA ESRARRLRAE GDALRERQEL
PAALEKYNQA LEMAPCKCSL IAQRAELCTL MKNYQQALHD ADILCRNKPH WPVGHYVKAK
ALSGLERTEE ALKEFLYCVA LNPEWSSMKK EAQKIMCEMF FPAFENVHDS LTAPFSSRTS
HTRLKPAFLS SINTQSAVED NSVAGSSKDS MFRLTKTPSQ ESDVFRSTDS SVTHHVLDLY
FDENKKSLGA ILSSLPGVGL KRKLSSDTRD LQSLDVPNKI LKKDGDVLPE NTTDTSSEIP
TTLVDASDFE CSLCMRLFYE PVTTPCGHTF CLKCLERCLD HNPLCPLCKE KLSEFLASRT
YKKTVLTEEL IVRYLPEELS ERKKVYDEEM KELSNLNKDV PIFVCTMAFP TIPCPLHVFE
PRYRLMIRRC METGTKQFGM CLADELKGFA DHGCILEIRD VKFFPDGRSV VDTVGVRRFR
VLSHGQRDGY NTANIEYLED KKSNPSGPAW YWWLLAVLPL ENRAQLAILA MTSLKDRLIA
IRRVLIFVTR KRPR
//
