ID H0ZIV5_TAEGU Unreviewed; 489 AA.
AC H0ZIV5;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Serine incorporator 4 {ECO:0000313|Ensembl:ENSTGUP00000010522.2};
GN Name=SERINC4 {ECO:0000313|Ensembl:ENSTGUP00000010522.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000010522.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000010522.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000010522.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TDE1 family.
CC {ECO:0000256|ARBA:ARBA00006665}.
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DR AlphaFoldDB; H0ZIV5; -.
DR Ensembl; ENSTGUT00000010633.2; ENSTGUP00000010522.2; ENSTGUG00000010186.2.
DR GeneTree; ENSGT01030000234623; -.
DR HOGENOM; CLU_029574_5_2_1; -.
DR OMA; IHNFWFL; -.
DR TreeFam; TF312881; -.
DR Proteomes; UP000007754; Chromosome 10.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR005016; TDE1/TMS.
DR PANTHER; PTHR10383; SERINE INCORPORATOR; 1.
DR PANTHER; PTHR10383:SF5; SERINE INCORPORATOR 4; 1.
DR Pfam; PF03348; Serinc; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..489
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5025534442"
FT TRANSMEM 33..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 86..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 436..460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 489 AA; 54675 MW; 298A50DB1E14052E CRC64;
MAGTAGRGHL LHPLLFQLCC GCHGLRVSTS TRILYTLLHV LASAVCCLML SRTVAQAITE
KVPFSVVLCQ HLPGGTDCEQ LVGSSAVYRV CFGTACFHLA QAALLLNVRS SSDCRAQLHN
GFWLLKLLVL VGLWAASFFI PEDNFIQAWH YTGVCGGFAF ILIQLVLITA FAHTWNKNWL
TGAAQDKRWY LAVLLATAAF YTLASAAFSF LYKFYTHPAA CHLNKALLAI NGSLCGIMSF
ISITPCVRLK QPRSGLLQSS IISCYVMYLT FSALSSRPPE RVLYQGQNLT VCFPGVRQDE
LQTEDTTVAV LGAAIMYACV LFACNEASYL AEVFGPLWMV KVYSFEFKKP SCCFCCPEKM
EEELRGTDQT CEQVEESARG QFIIQDEQDR VVYSYSAFHF VFFLASLYVM MTLTNWFSYE
NAVLETTFTH GSWSAFWVKV SSCWACVLLY LWLLLSPFCL HGSPQHRHSS TGPRIVRRRR
APQRIDVST
//
