ID H0ZML5_TAEGU Unreviewed; 839 AA.
AC H0ZML5;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=BICD cargo adaptor 1 {ECO:0000313|Ensembl:ENSTGUP00000011838.2};
GN Name=BICD1 {ECO:0000313|Ensembl:ENSTGUP00000011838.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000011838.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000011838.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000011838.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the BicD family.
CC {ECO:0000256|ARBA:ARBA00010061}.
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DR AlphaFoldDB; H0ZML5; -.
DR STRING; 59729.ENSTGUP00000011838; -.
DR Ensembl; ENSTGUT00000011967.2; ENSTGUP00000011838.2; ENSTGUG00000011484.2.
DR GeneTree; ENSGT00940000154471; -.
DR HOGENOM; CLU_014107_0_0_1; -.
DR InParanoid; H0ZML5; -.
DR OMA; KAEHDCE; -.
DR TreeFam; TF323833; -.
DR Proteomes; UP000007754; Chromosome 1A.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0005881; C:cytoplasmic microtubule; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0016020; C:membrane; IEA:Ensembl.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR GO; GO:0099503; C:secretory vesicle; IEA:Ensembl.
DR GO; GO:0005802; C:trans-Golgi network; IEA:Ensembl.
DR GO; GO:0008093; F:cytoskeletal anchor activity; IEA:Ensembl.
DR GO; GO:0034452; F:dynactin binding; IEA:Ensembl.
DR GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:Ensembl.
DR GO; GO:0019901; F:protein kinase binding; IEA:Ensembl.
DR GO; GO:0031267; F:small GTPase binding; IEA:Ensembl.
DR GO; GO:0072385; P:minus-end-directed organelle transport along microtubule; IEA:Ensembl.
DR GO; GO:1904781; P:positive regulation of protein localization to centrosome; IEA:Ensembl.
DR GO; GO:0048260; P:positive regulation of receptor-mediated endocytosis; IEA:Ensembl.
DR GO; GO:0033365; P:protein localization to organelle; IEA:Ensembl.
DR GO; GO:0070507; P:regulation of microtubule cytoskeleton organization; IEA:Ensembl.
DR GO; GO:0016032; P:viral process; IEA:Ensembl.
DR Gene3D; 6.10.250.2470; -; 1.
DR InterPro; IPR018477; BICD.
DR PANTHER; PTHR31233; BICAUDAL D FAMILY MEMBER; 1.
DR PANTHER; PTHR31233:SF3; PROTEIN BICAUDAL D HOMOLOG 1; 1.
DR Pfam; PF09730; BicD; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754}.
FT REGION 549..622
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 804..839
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 3..72
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 109..265
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 323..368
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 424..476
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 671..790
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 596..622
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 839 AA; 96437 MW; 1F1C6879FBE0D4C4 CRC64;
MAAEEVLQGA DHYKSEIERL TRELSETTHE KIQAAEYGLV VLEEKLTLKQ QYDELEAEYD
GLKQELEQLK EAFGQSFSVH RKVAEDGETR EETLLQESAS KEAYYLGKIL EMQNELKQSR
AVVTNVQAEN ERLTAIVQDL KENNEMVELQ RIRMKDEIRE YKFREARLLQ DYTELEEENI
TLQKLVSTLK QNQVEYEGLK HEIKRFEEET VLLNSQLEDA IRLKEIAEHQ LEEALETLKN
EREQKNNLRK ELSQYINLND SMYNNHINIS VDGLKFSEDG GEPNNDDKMN GHIHGPLVKL
NGDYRTPTSR KGESLHPVSD LFSELNISEI QKLKQQLMQV EREKAILLAN LQESQTQLEH
TKGALTEQHE RVHRLTEHVN AMRGLQSNKE LKVELDCEKG RDSGEEAHDY EVDINGLEIL
ECKYKVAVTE VIDLKAEIKA LKEKYNNYVE NYTEEKAKYE SRIQTYDEQV TSLEKSTKES
QEKMVHMEKE LQRMTSIANE NHNTLNTAQD ELVTFSEELA QLYHHVCLCN NETPNRVMLD
YYRQSRVTRS GSLKGPDDPR GLLSPRLARR GVASPVEART PTEQVTKEAA EPGKEQSPTK
TPSISPVITA PPSSPVSDTS DIRKEPMNIY NLNAIIRDQI KHLQKAVDRS LQLSRQRAAA
RELAPMIDKD KEALMEEILK LKSLLSTKRE QIATLRAVLK ANKQTAEVAL ANLKNKYENE
KAMVTETMTK LRNELKALKE DAATFSSLRA MFATRCDEYV TQLDEMQRQL AAAEDEKKTL
NSLLRMAIQQ KLALTQRLED LEFDHEQSRR SKGKLGKSKI GSPKIVSSLL PPYRHTAHN
//
