ID H0ZQF8_TAEGU Unreviewed; 732 AA.
AC H0ZQF8;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 67.
DE RecName: Full=Tudor domain-containing protein 3 {ECO:0000256|ARBA:ARBA00013421};
GN Name=TDRD3 {ECO:0000313|Ensembl:ENSTGUP00000012846.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000012846.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000012846.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000012846.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; H0ZQF8; -.
DR STRING; 59729.ENSTGUP00000015450; -.
DR Ensembl; ENSTGUT00000012992.2; ENSTGUP00000012846.2; ENSTGUG00000012476.2.
DR GeneTree; ENSGT00940000155487; -.
DR HOGENOM; CLU_022646_0_0_1; -.
DR TreeFam; TF316491; -.
DR Proteomes; UP000007754; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR CDD; cd20413; Tudor_TDRD3; 1.
DR CDD; cd14282; UBA_TDRD3; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 2.40.50.770; RecQ-mediated genome instability protein Rmi1, C-terminal domain; 1.
DR InterPro; IPR042470; RMI1_N_C_sf.
DR InterPro; IPR013894; RMI1_OB.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR047379; Tudor_TDRD3.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR InterPro; IPR041915; UBA_TDRD3.
DR PANTHER; PTHR13681; SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED; 1.
DR PANTHER; PTHR13681:SF24; TUDOR DOMAIN-CONTAINING PROTEIN 3; 1.
DR Pfam; PF08585; RMI1_N_C; 1.
DR Pfam; PF00567; TUDOR; 1.
DR Pfam; PF00627; UBA; 1.
DR SMART; SM01161; DUF1767; 1.
DR SMART; SM00333; TUDOR; 1.
DR SMART; SM00165; UBA; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS50304; TUDOR; 1.
DR PROSITE; PS50030; UBA; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754}.
FT DOMAIN 286..326
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT DOMAIN 644..704
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT REGION 240..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 326..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 399..544
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..260
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..357
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..430
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..476
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..544
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..584
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 732 AA; 82333 MW; C3F6E05F6D638B54 CRC64;
MAERARAALS ESGWCLSDEG IEACLSSSEK VNTNDIILVA LNTDLRTIGK KFLPSDINGG
KVEKLEGPCV LQIQKIRNVA APKDNEESQA APRMLRLQMT DGHTSCTAIE YSSMSKISLN
TPPGTKIKLS GVVEVRNGFL LLDDSNTAVL GGEVEHLIEK WELQRSLAKH NRSNIGTEGG
PPPFVPFGQK CASYVQVDSR DLDRRKTLQM TNAVKPVADN DEFEKQRTAA IAEVAKSKET
KTFGGGGGSS RSNLSVSTGG NRNRELFQKE KIAKPEGKNE GVYRELVDEK ALKHITEMGF
SKEAARQALM DNSNSLEAAL NFLLNNSKQK PIQGPPPRGK GKGRGRIRPE DEEELGNARP
SAPSTLFDFL ESKMGTLTVE EPKLQFQPTH QVQHKVMNTE QNGIKENHSR HVSRNDMRQP
RNEKPPRFQK DFQNSRQALE SGGLPRNRGP ERHSSLEHWT DEKNKSDRHY PRNDRSKDLS
YPISTHQSDS TFKKRDNNMQ NRVGKGVSFS EFKENSAAQD VTENNNQKRG KRENQTHNSE
NFCDRKARTI STEAFMVKRE QHFGVNNDYQ NPSRTDNFSA VPNGDTEHHQ KGRRVGPIKS
SGPTAIPSFD DKMLYYNTGP KRRTGPIKPE KILEPSSHME YGKSWRPGDE CFALYWEDNK
FYRAEIEALH SSGTTAVVKF SDYGNYEEVL LSNIRPVHAD TWAQSNTDVL YTGRKSEHLQ
AKKRLLWEKI TL
//
