ID H0ZRD4_TAEGU Unreviewed; 489 AA.
AC H0ZRD4;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=BEN domain containing 6 {ECO:0000313|Ensembl:ENSTGUP00000013177.2};
GN Name=BEND6 {ECO:0000313|Ensembl:ENSTGUP00000013177.2};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000013177.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000013177.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000013177.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR AlphaFoldDB; H0ZRD4; -.
DR STRING; 59729.ENSTGUP00000013177; -.
DR Ensembl; ENSTGUT00000013326.2; ENSTGUP00000013177.2; ENSTGUG00000012798.2.
DR GeneTree; ENSGT00390000016954; -.
DR HOGENOM; CLU_065590_0_0_1; -.
DR InParanoid; H0ZRD4; -.
DR OMA; NQGCRQD; -.
DR OrthoDB; 5314697at2759; -.
DR TreeFam; TF335394; -.
DR Proteomes; UP000007754; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR GO; GO:0045746; P:negative regulation of Notch signaling pathway; IEA:InterPro.
DR GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:InterPro.
DR Gene3D; 1.10.10.2590; BEN domain; 1.
DR InterPro; IPR018379; BEN_domain.
DR InterPro; IPR037496; BEND6-like.
DR PANTHER; PTHR35346; BEN DOMAIN-CONTAINING PROTEIN 6; 1.
DR PANTHER; PTHR35346:SF1; BEN DOMAIN-CONTAINING PROTEIN 6; 1.
DR Pfam; PF10523; BEN; 1.
DR SMART; SM01025; BEN; 1.
DR PROSITE; PS51457; BEN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007754}.
FT DOMAIN 277..373
FT /note="BEN"
FT /evidence="ECO:0000259|PROSITE:PS51457"
FT REGION 401..443
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 401..429
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 489 AA; 54843 MW; D7EE5AEC39AEE735 CRC64;
MKKFTLFDFV NDNSLQIGET SWIQDLPCDD NELERLLKPN EHVLVNWPVG ERKTEKHLVK
VVYMSDDPQE LVEMMQKILR ADEITKIQVL GKGKRKRIEM IFSESEDSDL DKEKGKMMKH
IKRKKSLQAP APANILSQLE TSLINKQREP YSGSNFLYSE SSSDDEEPLF QLSKVELCAK
IKSLKRKLTD TMRENCRLRQ SLVMLQVLPQ AVTHFEELVG MAEALLKGGV TSSTSSLHPH
AVWKASHNPL ADSYAAMHSN SSSPITLNVE EEEQQTEKQF KIEKWQIALC NKSKPQKFIN
DLMQALYTHE YMATHSLTGA KSSSSKDKAA KPAMNQNEVQ EIIGITKQLF PNTDDALIRR
MMGQKLNNCT KKPILSKDLN SGAFQKHSFC GSTAAPQGII SSAVPPCTQD QQDDDSPAAN
AQLQQNDSCL TPPPPTPEGF QHADMGRSEC LGLWLSCLSV LLPELKVLLA ESTTNMANKQ
LTNQIGKMK
//
