ID H0ZTH0_TAEGU Unreviewed; 959 AA.
AC H0ZTH0;
DT 22-FEB-2012, integrated into UniProtKB/TrEMBL.
DT 17-JUN-2020, sequence version 2.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
OS Taeniopygia guttata (Zebra finch) (Poephila guttata).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Taeniopygia.
OX NCBI_TaxID=59729 {ECO:0000313|Ensembl:ENSTGUP00000013916.2, ECO:0000313|Proteomes:UP000007754};
RN [1] {ECO:0000313|Ensembl:ENSTGUP00000013916.2, ECO:0000313|Proteomes:UP000007754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20360741; DOI=10.1038/nature08819;
RA Warren W.C., Clayton D.F., Ellegren H., Arnold A.P., Hillier L.W.,
RA Kunstner A., Searle S., White S., Vilella A.J., Fairley S., Heger A.,
RA Kong L., Ponting C.P., Jarvis E.D., Mello C.V., Minx P., Lovell P.,
RA Velho T.A., Ferris M., Balakrishnan C.N., Sinha S., Blatti C., London S.E.,
RA Li Y., Lin Y.C., George J., Sweedler J., Southey B., Gunaratne P.,
RA Watson M., Nam K., Backstrom N., Smeds L., Nabholz B., Itoh Y., Whitney O.,
RA Pfenning A.R., Howard J., Volker M., Skinner B.M., Griffin D.K., Ye L.,
RA McLaren W.M., Flicek P., Quesada V., Velasco G., Lopez-Otin C.,
RA Puente X.S., Olender T., Lancet D., Smit A.F., Hubley R., Konkel M.K.,
RA Walker J.A., Batzer M.A., Gu W., Pollock D.D., Chen L., Cheng Z.,
RA Eichler E.E., Stapley J., Slate J., Ekblom R., Birkhead T., Burke T.,
RA Burt D., Scharff C., Adam I., Richard H., Sultan M., Soldatov A.,
RA Lehrach H., Edwards S.V., Yang S.P., Li X., Graves T., Fulton L.,
RA Nelson J., Chinwalla A., Hou S., Mardis E.R., Wilson R.K.;
RT "The genome of a songbird.";
RL Nature 464:757-762(2010).
RN [2] {ECO:0000313|Ensembl:ENSTGUP00000013916.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; H0ZTH0; -.
DR STRING; 59729.ENSTGUP00000013916; -.
DR Ensembl; ENSTGUT00000014075.2; ENSTGUP00000013916.2; ENSTGUG00000013516.2.
DR GeneTree; ENSGT00940000155177; -.
DR HOGENOM; CLU_005187_0_0_1; -.
DR InParanoid; H0ZTH0; -.
DR OMA; SKWVNQA; -.
DR TreeFam; TF332702; -.
DR Proteomes; UP000007754; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00099; IgV; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 6.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR12207:SF25; IMMUNOGLOBULIN SUPERFAMILY MEMBER 2; 1.
DR PANTHER; PTHR12207; V-SET AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07686; V-set; 4.
DR SMART; SM00409; IG; 7.
DR SMART; SM00408; IGc2; 4.
DR SMART; SM00406; IGv; 6.
DR SUPFAM; SSF48726; Immunoglobulin; 7.
DR PROSITE; PS50835; IG_LIKE; 6.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007754};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..959
FT /note="Ig-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5025605728"
FT TRANSMEM 912..933
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..142
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 145..267
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 283..397
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 406..530
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 629..736
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 762..880
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 959 AA; 105896 MW; B56ED56E43C83FC8 CRC64;
MGLAQCLAAA FLFLLLGLTA GQRVVTVQEG PLYRVRGSHV TLWCKVSGYQ GPAEQNFQWS
IYLPSAPERE VQIVSTVDPS FPYAIYTQRV RGRGIFVERL QGDAVLLHIT ELQDRDAGQY
ECHTPNTDER YFGSYSARTN LTVIPDTLSA SLAPQALSHM EGDAVELTCE VSKSTAQHTH
LSVGWYLLQG AGEHHAKEIL TLSKDFILKP GPSYEQRFLE GDVQLNKVGN TTYKLIFREV
KPSDQGQLYC EAAEWIEDPD KTWKDISRRQ TERTRLAVLG QGSDLSVDIA AAEPSLSEGD
TLQLTCVLEA PKNSNFKVIW LLNDTEVARV DPHGVLICEE EYEERAKLGQ LRAFKPSNTI
YVLTITEVGL KDKGTYQCSV SEMKTPGDLH SIQTVVSSGI QVNVKPIESR MRLAVSTSTP
RVTAGEPLIL RCEVQGATGP VSLRWWHLPP QRPGHRVLVA TMEQDGSLSL GSAYQDGRAR
GSLRLQKESS GTFTLVIPSA LEDDGGQYRC EATQWSRGRS WTGKGEAAVT VSSMGLGLHA
TLRSRTASVS YGQSFELFCQ VDASYALEEG KAQLVKTGTS FRLHIHSALP ANEGTYQCEV
EVWRRNILPL GQSAASTSSN AVGIKVVLPE SKLQVATTDS SVEIASGNAA IECRIVFAQN
NSQFAATWYL LPPLAGATPL QILRANYSGI LEYGSEFSSP AQKSRFLSHR VSSNIFQLQI
LSANLGDRGR YYCVVEEWLW LVDGWYKLGE GTSGRTTLKF KPSERELQMD KTNHSLSARE
GEEATLPCRL QGAPLPGSQL SATWFQVRSS GRDSALLALQ HDGTVEYPEE RLAARLYLRR
RSAGDFSLTL SSVERGDAGA YYCQLQEWQQ QSQGKDWAVQ ALACSGYTQL TTIPPESTVV
SRICSSPPLL NFILYLPLVL ILLLALALFC WYCKSRKNKK GNITGWMMEL EGNEEAKKT
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