ID H1PIY3_9FIRM Unreviewed; 548 AA.
AC H1PIY3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=UmuC domain-containing protein {ECO:0000259|PROSITE:PS50173};
GN ORFNames=HMPREF0380_00141 {ECO:0000313|EMBL:EHO86793.1};
OS Eubacterium infirmum F0142.
OC Bacteria; Bacillota; Clostridia; Eubacteriales;
OC Eubacteriales Family XIII. Incertae Sedis.
OX NCBI_TaxID=883109 {ECO:0000313|EMBL:EHO86793.1, ECO:0000313|Proteomes:UP000004504};
RN [1] {ECO:0000313|EMBL:EHO86793.1, ECO:0000313|Proteomes:UP000004504}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0142 {ECO:0000313|EMBL:EHO86793.1,
RC ECO:0000313|Proteomes:UP000004504};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Izard J., Ganesan A.,
RA Baranova O.V., Blanton J.M., Tanner A.C., Dewhirst F.E., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Chapman S.B., Gearin G., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Heiman D., Howarth C., Larimer J., Lui A.,
RA MacDonald P.J.P., McCowen C., Montmayeur A., Murphy C., Neiman D.,
RA Pearson M., Priest M., Roberts A., Saif S., Shea T., Sisk P., Stolte C.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Eubacterium infirmum F0142.";
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945}.
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DR EMBL; AGWI01000005; EHO86793.1; -; Genomic_DNA.
DR AlphaFoldDB; H1PIY3; -.
DR STRING; 883109.HMPREF0380_00141; -.
DR PATRIC; fig|883109.3.peg.141; -.
DR eggNOG; COG0389; Bacteria.
DR HOGENOM; CLU_012348_5_1_9; -.
DR Proteomes; UP000004504; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0009432; P:SOS response; IEA:UniProt.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR11076; DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11076:SF35; DNA REPAIR PROTEIN HOMOLOG YOBH; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000004504}.
FT DOMAIN 5..233
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT REGION 460..480
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 460..478
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 548 AA; 61638 MW; B36EB33EBFECF39F CRC64;
MKKTYISIDL KSFYASVECM ERGLDPLNTN LVVADAARTQ KTICLAVSPS LKSYGIPGRA
RLFEVEQKVK EANARRRAKV PKNMIEGKSV IASELNENPR LAMDYIAAKP RMALYMSKST
QIYDIYLRYI APEDIYAYSV DEVFIDASAY LKTYGLSGHD FARLLIRAVF EKTGITATAG
IGTNLYLCKI AMDIGAKHTE ADADGVRIAE LDEYSYRRLL WEHRPITDFW RVGRGYAKKL
AKKSLFTMGD IARCSLGKSS DYYNEDLLYK MFGVNAELLI DHAWGYEPCT LTEIKSYRPQ
RKSLVSGQVL QSAYTYDKTR IVVREMMELL ALDLVDKGLL TNQIVLTVGY DIENLSDPER
RKAYKGEVTI DGYGREIPKH AHGTGNLPFS TASTKLTADC VLEVFDRVVD ENLLTRRISI
TANNLVTEDE YKREGEKKSA EPEQLSMFDM LVNSDEPIKA EDLPSEEPSD DRLRSKDLAP
VRSVAVESEA ELGDKDISED VLEKEKQVQE AMLKIKKRFG KNAILKGTNL QEGATAKERN
AQIGGHKA
//
