ID   H1Q345_9BACT            Unreviewed;       274 AA.
AC   H1Q345;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   24-JAN-2024, entry version 41.
DE   RecName: Full=DUF2520 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=HMPREF9140_01333 {ECO:0000313|EMBL:EHO69643.1};
OS   Prevotella micans F0438.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Prevotella.
OX   NCBI_TaxID=883158 {ECO:0000313|EMBL:EHO69643.1, ECO:0000313|Proteomes:UP000016023};
RN   [1] {ECO:0000313|EMBL:EHO69643.1, ECO:0000313|Proteomes:UP000016023}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0438 {ECO:0000313|EMBL:EHO69643.1,
RC   ECO:0000313|Proteomes:UP000016023};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Izard J., Baranova O.V.,
RA   Blanton J.M., Wade W.G., Dewhirst F.E., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA   Berlin A., Chapman S.B., Gearin G., Goldberg J., Griggs A., Gujja S.,
RA   Hansen M., Heiman D., Howarth C., Larimer J., Lui A., MacDonald P.J.P.,
RA   McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Prevotella micans F0438.";
RL   Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHO69643.1}.
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DR   EMBL; AGWK01000036; EHO69643.1; -; Genomic_DNA.
DR   AlphaFoldDB; H1Q345; -.
DR   STRING; 883158.HMPREF9140_01333; -.
DR   PATRIC; fig|883158.3.peg.1335; -.
DR   eggNOG; COG5495; Bacteria.
DR   HOGENOM; CLU_055635_1_1_10; -.
DR   Proteomes; UP000016023; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 1.10.1040.20; ProC-like, C-terminal domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR018931; DUF2520.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR028939; P5C_Rdtase_cat_N.
DR   InterPro; IPR037108; TM1727-like_C_sf.
DR   PANTHER; PTHR40459; CONSERVED HYPOTHETICAL ALANINE AND LEUCINE RICH PROTEIN; 1.
DR   PANTHER; PTHR40459:SF1; CONSERVED HYPOTHETICAL ALANINE AND LEUCINE RICH PROTEIN; 1.
DR   Pfam; PF10728; DUF2520; 1.
DR   Pfam; PF03807; F420_oxidored; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000016023}.
FT   DOMAIN          16..92
FT                   /note="Pyrroline-5-carboxylate reductase catalytic N-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03807"
FT   DOMAIN          140..265
FT                   /note="DUF2520"
FT                   /evidence="ECO:0000259|Pfam:PF10728"
SQ   SEQUENCE   274 AA;  30445 MW;  91F06EA68C36F4E9 CRC64;
     MGVLSRCLLN FAAIMKIVLI GAGNLATHIG GALQRAGHEI TQVYSRTIEA AAELAEKLGA
     SHTNCIEMIV RDADVYIFAV TDAALTEIIH EVCNGRENGL MLHTSGSTPM DCFRGMAKRY
     GVLYPLQTFS KCREIEFTNV PLFIEGCDAQ VEREIDLLAD GISHNHRHLD SADRRYLHLS
     AVWACNFVNH CYDIAAGILG QRDIPFDVLL PLIDETAAKV HRLPPNKAQT GPAVRFDENI
     IRSQAQLMSG DSRLKDLYER MSTSIHQRNK KQQS
//