ID   H1S0S1_9BURK            Unreviewed;       294 AA.
AC   H1S0S1;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   24-JAN-2024, entry version 42.
DE   SubName: Full=Regulatory protein IclR {ECO:0000313|EMBL:EHP43930.1};
GN   ORFNames=OR16_06064 {ECO:0000313|EMBL:EHP43930.1};
OS   Cupriavidus basilensis OR16.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=1127483 {ECO:0000313|EMBL:EHP43930.1, ECO:0000313|Proteomes:UP000005808};
RN   [1] {ECO:0000313|EMBL:EHP43930.1, ECO:0000313|Proteomes:UP000005808}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OR16 {ECO:0000313|EMBL:EHP43930.1,
RC   ECO:0000313|Proteomes:UP000005808};
RX   PubMed=22461549; DOI=10.1128/JB.06752-11;
RA   Cserhati M., Kriszt B., Szoboszlay S., Toth A., Szabo I., Tancsics A.,
RA   Nagy I., Horvath B., Nagy I., Kukolya J.;
RT   "De Novo Genome Project of Cupriavidus basilensis OR16.";
RL   J. Bacteriol. 194:2109-2110(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHP43930.1}.
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DR   EMBL; AHJE01000015; EHP43930.1; -; Genomic_DNA.
DR   RefSeq; WP_006156989.1; NZ_AHJE01000015.1.
DR   AlphaFoldDB; H1S0S1; -.
DR   PATRIC; fig|1127483.3.peg.1212; -.
DR   OrthoDB; 5401369at2; -.
DR   Proteomes; UP000005808; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR   InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR   PANTHER; PTHR30136:SF33; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR   Pfam; PF09339; HTH_IclR; 1.
DR   Pfam; PF01614; IclR; 1.
DR   SMART; SM00346; HTH_ICLR; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51077; HTH_ICLR; 1.
DR   PROSITE; PS51078; ICLR_ED; 1.
PE   4: Predicted;
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          45..107
FT                   /note="HTH iclR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51077"
FT   DOMAIN          108..291
FT                   /note="IclR-ED"
FT                   /evidence="ECO:0000259|PROSITE:PS51078"
FT   REGION          1..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   294 AA;  31683 MW;  07FFAEF5EB88AB48 CRC64;
     MKRTSSIPLS PTSAPGGAHA AAVRTADAPY DGGQQDAERD DRNFVTALAR GLDLLRAFGP
     HDDYLGNAEL ARRAGIPRPT VSRLTYTLTS LGYLIYSASL EKYRLGQGAM VLGQRYLAGS
     GIREIAQPLM QSLAFATDCT VALATSDRHE MVYLEVCQPR GALVMRLAPG SRLPTATSAI
     GRAWLSGLEP ERRAAVLADL ERHYGARWPA IRIKLERALR DYAKRGFCLA HAEWDRTVSG
     AAAPVVLEGG AEVLAINIGG AATRLTPEIL DGNLGPRIRE LAEALQSRLW QGRG
//