ID   H1S5G5_9BURK            Unreviewed;       398 AA.
AC   H1S5G5;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   24-JAN-2024, entry version 41.
DE   SubName: Full=IclR family transcriptional regulator {ECO:0000313|EMBL:EHP42332.1};
DE   Flags: Fragment;
GN   ORFNames=OR16_15424 {ECO:0000313|EMBL:EHP42332.1};
OS   Cupriavidus basilensis OR16.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=1127483 {ECO:0000313|EMBL:EHP42332.1, ECO:0000313|Proteomes:UP000005808};
RN   [1] {ECO:0000313|EMBL:EHP42332.1, ECO:0000313|Proteomes:UP000005808}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OR16 {ECO:0000313|EMBL:EHP42332.1,
RC   ECO:0000313|Proteomes:UP000005808};
RX   PubMed=22461549; DOI=10.1128/JB.06752-11;
RA   Cserhati M., Kriszt B., Szoboszlay S., Toth A., Szabo I., Tancsics A.,
RA   Nagy I., Horvath B., Nagy I., Kukolya J.;
RT   "De Novo Genome Project of Cupriavidus basilensis OR16.";
RL   J. Bacteriol. 194:2109-2110(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHP42332.1}.
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DR   EMBL; AHJE01000036; EHP42332.1; -; Genomic_DNA.
DR   AlphaFoldDB; H1S5G5; -.
DR   PATRIC; fig|1127483.3.peg.3095; -.
DR   Proteomes; UP000005808; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 3.30.450.40; -; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR   InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR   PANTHER; PTHR30136:SF33; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR   Pfam; PF09339; HTH_IclR; 1.
DR   Pfam; PF01614; IclR; 1.
DR   SMART; SM00346; HTH_ICLR; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 2.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS51077; HTH_ICLR; 1.
DR   PROSITE; PS51078; ICLR_ED; 2.
PE   4: Predicted;
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          1..164
FT                   /note="IclR-ED"
FT                   /evidence="ECO:0000259|PROSITE:PS51078"
FT   DOMAIN          151..213
FT                   /note="HTH iclR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51077"
FT   DOMAIN          214..397
FT                   /note="IclR-ED"
FT                   /evidence="ECO:0000259|PROSITE:PS51078"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EHP42332.1"
SQ   SEQUENCE   398 AA;  43717 MW;  5DC83B5F236C3697 CRC64;
     GSLGLRDRLQ MVYVETSRGH DAIAFRPDIG ASLPMLPTAI GRAWLCQASP GEREPVLAAL
     RASDAEQWQA HAAALDAAAR DFATLGFCLS RGEWQRDVHA VAVPMRAEID GEILVFNCGA
     PSARMTCDAS QVTPRGTPVA DEPDTGDRQF ATTLAHGIDI LLAYRPGESL LGNKEFAQRT
     GQSRPAVARL THTLTVLGYL RRDAAQAKYR LGAPVLSLGY PLLASMHIRQ IARPLMKELA
     DRIGGAVSLG MRDRTQMIYV ETARSTDSLV VTPDIGAALP MLTTAIGKAW LCKAPAEERE
     SVLNRLRLQD PDAFLRFQPQ LSRLRLDFEA KGYCVNRGEW RSDVYAFAVP LFRPVDSQWL
     IFNCGVSAQA RPFATREREV TPGLLDLARN VERLLGMR
//