ID   H1SE36_9BURK            Unreviewed;       324 AA.
AC   H1SE36;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   SubName: Full=Zinc-containing alcohol dehydrogenase superfamily protein {ECO:0000313|EMBL:EHP39295.1};
GN   ORFNames=OR16_32693 {ECO:0000313|EMBL:EHP39295.1};
OS   Cupriavidus basilensis OR16.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=1127483 {ECO:0000313|EMBL:EHP39295.1, ECO:0000313|Proteomes:UP000005808};
RN   [1] {ECO:0000313|EMBL:EHP39295.1, ECO:0000313|Proteomes:UP000005808}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OR16 {ECO:0000313|EMBL:EHP39295.1,
RC   ECO:0000313|Proteomes:UP000005808};
RX   PubMed=22461549; DOI=10.1128/JB.06752-11;
RA   Cserhati M., Kriszt B., Szoboszlay S., Toth A., Szabo I., Tancsics A.,
RA   Nagy I., Horvath B., Nagy I., Kukolya J.;
RT   "De Novo Genome Project of Cupriavidus basilensis OR16.";
RL   J. Bacteriol. 194:2109-2110(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EHP39295.1}.
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DR   EMBL; AHJE01000098; EHP39295.1; -; Genomic_DNA.
DR   RefSeq; WP_006162442.1; NZ_AHJE01000098.1.
DR   AlphaFoldDB; H1SE36; -.
DR   PATRIC; fig|1127483.3.peg.6520; -.
DR   OrthoDB; 9805883at2; -.
DR   Proteomes; UP000005808; Unassembled WGS sequence.
DR   GO; GO:0003960; F:NADPH:quinone reductase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd05286; QOR2; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   InterPro; IPR047618; QOR-like.
DR   InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR   PANTHER; PTHR48106; QUINONE OXIDOREDUCTASE PIG3-RELATED; 1.
DR   PANTHER; PTHR48106:SF13; QUINONE OXIDOREDUCTASE-RELATED; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE   4: Predicted;
KW   NADP {ECO:0000256|ARBA:ARBA00022857};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          11..322
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   324 AA;  34423 MW;  8B029D42A1FAFF13 CRC64;
     MSKAIRIFET GGPEVMQWVD VEVGDPGPGE VRVRHEAVGL NYIDVYFRTG LYKQPLPAGL
     GMEGAGVVEA VGAGVGHLSV GDRVAYAGRP TGAYAQVRVM PADIVVRLPD AISFEQGAAM
     MLQGLTTQYL LRDSYRVQAG DTVLLHAAAG GVGLIASQWL KALGATVIGT AGSDEKAALA
     RAHGCDHTIV YTRESFVDKV KEITGGKGVA AVYDSVGKDT FNGSLDCLKP RGTMVVFGNA
     SGPVPPFDLS VLGNKGSLRI TRPTLMTYVV HRELLEPMAA ELFEMVTSGR VKIEVRQRYA
     LADVAQAHRD LEGRKTTGTT VLLP
//