ID H1SIG3_9BURK Unreviewed; 485 AA.
AC H1SIG3;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Periplasmic protease {ECO:0000313|EMBL:EHP37684.1};
GN ORFNames=OR16_41419 {ECO:0000313|EMBL:EHP37684.1};
OS Cupriavidus basilensis OR16.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=1127483 {ECO:0000313|EMBL:EHP37684.1, ECO:0000313|Proteomes:UP000005808};
RN [1] {ECO:0000313|EMBL:EHP37684.1, ECO:0000313|Proteomes:UP000005808}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OR16 {ECO:0000313|EMBL:EHP37684.1,
RC ECO:0000313|Proteomes:UP000005808};
RX PubMed=22461549; DOI=10.1128/JB.06752-11;
RA Cserhati M., Kriszt B., Szoboszlay S., Toth A., Szabo I., Tancsics A.,
RA Nagy I., Horvath B., Nagy I., Kukolya J.;
RT "De Novo Genome Project of Cupriavidus basilensis OR16.";
RL J. Bacteriol. 194:2109-2110(2012).
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHP37684.1}.
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DR EMBL; AHJE01000211; EHP37684.1; -; Genomic_DNA.
DR RefSeq; WP_006164637.1; NZ_AHJE01000211.1.
DR AlphaFoldDB; H1SIG3; -.
DR PATRIC; fig|1127483.3.peg.8219; -.
DR OrthoDB; 9758917at2; -.
DR Proteomes; UP000005808; Unassembled WGS sequence.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00987; PDZ_serine_protease; 2.
DR Gene3D; 2.30.42.10; -; 2.
DR Gene3D; 2.40.10.120; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011782; Pept_S1C_Do.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR001940; Peptidase_S1C.
DR NCBIfam; TIGR02037; degP_htrA_DO; 1.
DR PANTHER; PTHR22939; SERINE PROTEASE FAMILY S1C HTRA-RELATED; 1.
DR PANTHER; PTHR22939:SF129; SERINE PROTEASE HTRA2, MITOCHONDRIAL; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF17820; PDZ_6; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 2.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:EHP37684.1};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 280..341
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 399..475
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT ACT_SITE 133
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
FT ACT_SITE 163
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
FT ACT_SITE 236
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
SQ SEQUENCE 485 AA; 50312 MW; 0E1B954095A62016 CRC64;
MIRQTLARSA IGIAALAALA GGYTYLQKEV ITPGYAAQAP LTAPAQPLAA PTDFSNIVEQ
YGPAVVNISV TARAQRTSAQ VPQGMDPDDP LFQFFKRFGP QFQGPQNGQQ QLVRGLGSGF
IVSPEGLILT NAHVVDGAQE VTVKLTDRRE FKAKVLGADA QTDVAVIKID AKDLPTVRLG
DPSRVRVGEP VLAIGSPYGF ENTVTGGIVS AKSRSLPDDT YVPFIQTDVA VNPGNSGGPL
FNQRGEVIGI NSQIYSQTGG YQGLSFSIPI DVATKVQSQL VAHGKVTRGR LGIGVQEVNQ
ALAQSFGLPK PSGALVNSVE PDSPAAKAGL KPGDVIVQLG NDVIDHSGDL PEHVADIAPG
TQTSLKVIRK GEPLTLTVKV GTAKDAAVAG KNPANDAGGK LGLAVRPLSP TERRDSGIDG
GLVVEDVAGP AAKVGIQPGD VILSINGTPI SSADQLRALV AKSGKQVALL VQRDDARIFI
PLDLG
//
