ID   H1V3K4_COLHI            Unreviewed;       887 AA.
AC   H1V3K4;
DT   21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT   21-MAR-2012, sequence version 1.
DT   24-JAN-2024, entry version 46.
DE   SubName: Full=WD repeat domain-containing protein {ECO:0000313|EMBL:CCF34806.1};
GN   ORFNames=CH063_06722 {ECO:0000313|EMBL:CCF34806.1};
OS   Colletotrichum higginsianum (strain IMI 349063) (Crucifer anthracnose
OS   fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC   Colletotrichum destructivum species complex.
OX   NCBI_TaxID=759273 {ECO:0000313|EMBL:CCF34806.1, ECO:0000313|Proteomes:UP000007174};
RN   [1] {ECO:0000313|Proteomes:UP000007174}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IMI 349063 {ECO:0000313|Proteomes:UP000007174};
RX   PubMed=22885923; DOI=10.1038/ng.2372;
RA   O'Connell R.J., Thon M.R., Hacquard S., Amyotte S.G., Kleemann J.,
RA   Torres M.F., Damm U., Buiate E.A., Epstein L., Alkan N., Altmueller J.,
RA   Alvarado-Balderrama L., Bauser C.A., Becker C., Birren B.W., Chen Z.,
RA   Choi J., Crouch J.A., Duvick J.P., Farman M.A., Gan P., Heiman D.,
RA   Henrissat B., Howard R.J., Kabbage M., Koch C., Kracher B., Kubo Y.,
RA   Law A.D., Lebrun M.-H., Lee Y.-H., Miyara I., Moore N., Neumann U.,
RA   Nordstroem K., Panaccione D.G., Panstruga R., Place M., Proctor R.H.,
RA   Prusky D., Rech G., Reinhardt R., Rollins J.A., Rounsley S., Schardl C.L.,
RA   Schwartz D.C., Shenoy N., Shirasu K., Sikhakolli U.R., Stueber K.,
RA   Sukno S.A., Sweigard J.A., Takano Y., Takahara H., Trail F.,
RA   van der Does H.C., Voll L.M., Will I., Young S., Zeng Q., Zhang J.,
RA   Zhou S., Dickman M.B., Schulze-Lefert P., Ver Loren van Themaat E.,
RA   Ma L.-J., Vaillancourt L.J.;
RT   "Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered
RT   by genome and transcriptome analyses.";
RL   Nat. Genet. 44:1060-1065(2012).
CC   -!- SIMILARITY: Belongs to the peptidase M20A family.
CC       {ECO:0000256|ARBA:ARBA00006247}.
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DR   EMBL; CACQ02001282; CCF34806.1; -; Genomic_DNA.
DR   AlphaFoldDB; H1V3K4; -.
DR   STRING; 759273.H1V3K4; -.
DR   EnsemblFungi; CCF34806; CCF34806; CH063_06722.
DR   VEuPathDB; FungiDB:CH63R_08637; -.
DR   eggNOG; KOG2276; Eukaryota.
DR   HOGENOM; CLU_008535_0_0_1; -.
DR   Proteomes; UP000007174; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:EnsemblFungi.
DR   GO; GO:0061672; C:glutathione hydrolase complex; IEA:EnsemblFungi.
DR   GO; GO:0034399; C:nuclear periphery; IEA:EnsemblFungi.
DR   GO; GO:0036374; F:glutathione hydrolase activity; IEA:EnsemblFungi.
DR   GO; GO:0042802; F:identical protein binding; IEA:EnsemblFungi.
DR   GO; GO:0006751; P:glutathione catabolic process; IEA:EnsemblFungi.
DR   Gene3D; 3.30.70.360; -; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR001261; ArgE/DapE_CS.
DR   InterPro; IPR017149; GSH_degradosome_Dug2.
DR   InterPro; IPR002933; Peptidase_M20.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR43270; BETA-ALA-HIS DIPEPTIDASE; 1.
DR   PANTHER; PTHR43270:SF8; DI- AND TRIPEPTIDASE DUG2-RELATED; 1.
DR   Pfam; PF01546; Peptidase_M20; 1.
DR   Pfam; PF00400; WD40; 3.
DR   PIRSF; PIRSF037237; Peptidase_WD_repeats_DUG2; 1.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR   PROSITE; PS00758; ARGE_DAPE_CPG2_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 3.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT   REPEAT          30..65
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          72..103
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          231..250
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
SQ   SEQUENCE   887 AA;  97957 MW;  67B10048CAE3715C CRC64;
     MPSVIAPSDL STTLSDTEDC PQVAPELLHN LKHDSSVLAL AVSAENERIY AGTQDGEIVV
     WSLATFHQER IVQAHKRSVL SLYLTPDGSM LFSSAGDPII NVWCPKTMNR LYEIYSTYDV
     GDIFSVAYSA QHDTVYVGAQ NTSIQWVSLT DPNNRVTHDS SQHPDRRNHR FFDSRAVGGT
     STPRRNDERW ALIPRSEKVV EIHPGALQMF AHYGYVYSML MAKGPTVLVE PDEEVLISGG
     GDGTIKLWKL GAEGDDQAAE NDREPGLQEL MSLGADDAES VMSLAIDGSF LYAGKLQGVI
     ELWDLDTKSK LRVIKGHRGD VMTLQMSWGY LLSASRSGSA SKHTTAHYGK YQDKRAANIS
     QKYQCVARWK AHEGKVLSSA VTTYNNRQYY ITGANDDDVA IWHIDCSSLE EQKEVDEAND
     VMIKTLGEFV SYRTVSSRPE FAEDCRRGAT FLGSLFKRLG GHVEMLSTES SPHNPVVLAK
     FDGTLEPAEK RKKILFYGHY DVVPADTKKG KWETDPFQMK GINGYLYGRG VSDNKGPIMA
     ALYAVTDLLQ AKKLANDIIF LIEGEEESAS RGFREIVRKN KDLIGDVDYI LLANSYWLDD
     EVPCLTYGLR GVLHATVCVD SHLPDQHSGV DGSYMNDEPL SDLTSTLSKL KGPGNKVLIP
     GFYDDIFPVT AEEETRYDDI ASTLMRQNPE KGPADKLKGA LMARWREPNL TIHRYKVSGP
     DGSLVSSHAS ANISLRLVPG QEVNDVIASL NSYLESEFAT LESKNSLTIK VDNKAEPWLG
     DPTNAIFQTL EEAIIQAWSS VFEGGAADDG AEGAAAETKE KKPKKPLYIR EGGSIPAIRF
     LEKEFSAPAA HLPCGQASDS AHLDNERLRV LNLVKSREII GSLFARL
//