ID H1VKA2_COLHI Unreviewed; 760 AA.
AC H1VKA2;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=CH063_11166 {ECO:0000313|EMBL:CCF40655.1};
OS Colletotrichum higginsianum (strain IMI 349063) (Crucifer anthracnose
OS fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum destructivum species complex.
OX NCBI_TaxID=759273 {ECO:0000313|EMBL:CCF40655.1, ECO:0000313|Proteomes:UP000007174};
RN [1] {ECO:0000313|Proteomes:UP000007174}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMI 349063 {ECO:0000313|Proteomes:UP000007174};
RX PubMed=22885923; DOI=10.1038/ng.2372;
RA O'Connell R.J., Thon M.R., Hacquard S., Amyotte S.G., Kleemann J.,
RA Torres M.F., Damm U., Buiate E.A., Epstein L., Alkan N., Altmueller J.,
RA Alvarado-Balderrama L., Bauser C.A., Becker C., Birren B.W., Chen Z.,
RA Choi J., Crouch J.A., Duvick J.P., Farman M.A., Gan P., Heiman D.,
RA Henrissat B., Howard R.J., Kabbage M., Koch C., Kracher B., Kubo Y.,
RA Law A.D., Lebrun M.-H., Lee Y.-H., Miyara I., Moore N., Neumann U.,
RA Nordstroem K., Panaccione D.G., Panstruga R., Place M., Proctor R.H.,
RA Prusky D., Rech G., Reinhardt R., Rollins J.A., Rounsley S., Schardl C.L.,
RA Schwartz D.C., Shenoy N., Shirasu K., Sikhakolli U.R., Stueber K.,
RA Sukno S.A., Sweigard J.A., Takano Y., Takahara H., Trail F.,
RA van der Does H.C., Voll L.M., Will I., Young S., Zeng Q., Zhang J.,
RA Zhou S., Dickman M.B., Schulze-Lefert P., Ver Loren van Themaat E.,
RA Ma L.-J., Vaillancourt L.J.;
RT "Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered
RT by genome and transcriptome analyses.";
RL Nat. Genet. 44:1060-1065(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
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DR EMBL; CACQ02004215; CCF40655.1; -; Genomic_DNA.
DR AlphaFoldDB; H1VKA2; -.
DR STRING; 759273.H1VKA2; -.
DR EnsemblFungi; CCF40655; CCF40655; CH063_11166.
DR VEuPathDB; FungiDB:CH63R_07584; -.
DR eggNOG; KOG0890; Eukaryota.
DR HOGENOM; CLU_318224_0_0_1; -.
DR Proteomes; UP000007174; Unassembled WGS sequence.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR012993; UME.
DR PANTHER; PTHR11139; ATAXIA TELANGIECTASIA MUTATED ATM -RELATED; 1.
DR PANTHER; PTHR11139:SF124; SERINE_THREONINE-PROTEIN KINASE MEC1; 1.
DR Pfam; PF08064; UME; 1.
DR SMART; SM00802; UME; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:CCF40655.1};
KW Transferase {ECO:0000313|EMBL:CCF40655.1}.
FT DOMAIN 314..421
FT /note="UME"
FT /evidence="ECO:0000259|SMART:SM00802"
SQ SEQUENCE 760 AA; 85277 MW; 76A37AF6D9412F0C CRC64;
MRRIINHADI TQLIDLETSA LGQWCLQSLH SSVRELRIAS GRALPLFLAD ASSDTLDPAV
VKRNRKNALS LLKAASEKDA VIFHESGILA WSQLGRVVTG DELNLVLHKL LEYLGSNNSL
IAACAFNEIL GLATALKTTP RRLFEPFWRN LAYFAVKDMV SRPQMTRAIA DLLQISVTDF
LLLIQTHAMP WLVLMKKKDV IQKIAEARGE KDVWVPILDT VNAGPILALL LVQDVHNIEQ
FVMSRLIEVA SHLESFSLVE LMQAEVVTIV LELLKAVGEA DETRKPRIIE ALTSFCSMMM
VANKESRPKK GNTIGRFLES YILGLMARLA DVINDMPLVS PPVEEQRRCV RAMEEMIRLC
KTYVRIARPQ ISACLLSALD QDDLREVAFS CWAALLTYLD SEDVEVLLET TFFVIGHYWP
LFNDSSRRMA KNLITTLMTD FDTVLHENIS KLPSLAHVPE LADIEAQLSA IRPPLDSSKA
FALFAERISH ENSGVVLQAL AELETYLKQS GGFLQTSTIS QQPDPVVSTV LRALLDCASK
YSSSQLEIAS LCTQCIGLVG CLDSNRVEAP REQKSMVILS NFENSEETTD FVLFTLENIL
VKAFLSTTDT KLQGFLAFAM QELLSRVDIK AACAMKNTGQ RDGGSIYRKW LALPESVRMI
LTPFLTSKYI LMTMTMATIE YPIFRPGKPY GNWMRSFNMD LLRKGQNAYA DLIFEPLCRT
IRVKDLAVAE FLMPYLVLHV IIGHRSSRKE RDNVIANERT
//
