ID H1Y2V5_9SPHI Unreviewed; 954 AA.
AC H1Y2V5;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=Mucpa_4410 {ECO:0000313|EMBL:EHQ28500.1};
OS Mucilaginibacter paludis DSM 18603.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Mucilaginibacter.
OX NCBI_TaxID=714943 {ECO:0000313|EMBL:EHQ28500.1, ECO:0000313|Proteomes:UP000002774};
RN [1] {ECO:0000313|EMBL:EHQ28500.1, ECO:0000313|Proteomes:UP000002774}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 18603 {ECO:0000313|EMBL:EHQ28500.1,
RC ECO:0000313|Proteomes:UP000002774};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L.,
RA Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Held B.,
RA Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V.,
RA Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Tindall B., Brambilla E.,
RA Klenk H.-P., Eisen J.A.;
RT "The permanent draft genome of Mucilaginibacter paludis DSM 18603.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM001403; EHQ28500.1; -; Genomic_DNA.
DR RefSeq; WP_008509356.1; NZ_CM001403.1.
DR AlphaFoldDB; H1Y2V5; -.
DR STRING; 714943.Mucpa_4410; -.
DR eggNOG; COG0178; Bacteria.
DR HOGENOM; CLU_001370_0_2_10; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000002774; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd03271; ABC_UvrA_II; 1.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002774};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 614..942
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 954 AA; 106894 MW; 6BED49CDCC225D2D CRC64;
MIEKPVDLGE QSEVEVYGAR VHNLKNIDVS FPRNQLVVIT GLSGSGKSSL AFDTIYAEGQ
RRYMETFSAY SRQFMGGMER PDVDKVSGLS PVIAIEQKTT SKNPRSTVGT ITEIYDFMRL
LYARSGEAYS YVSGEKMERM SEEQILKTVL EKFGEQPINI LAPAVKGRKG HYRELFEQIR
KQGFLKVWVD GEMLNVEPKM QVDRYKIHDI DIVVDRLVVT DKDIKRLQTS IQSALKLAKG
IIRIADKENN LYYFSKYLMD PVSGISYDEP QPNTFSFNSP YGACERCDGL GYIFEIDEAS
VIPNPKLSIM NGGLAPLGEY RETWIFQVLK ALAKKYEFAL STPLEKLPRE TLEMILNGSH
ELVTVPVEYN KWNVQNYQIT FDGIIKMLEE QQEKRGEDAL GDMEAYRVLK SCPVCDGARL
KKESLHFKVD GKNIFELASM DINTLRDWFT GLEDRLNERQ NVIAKEILKE IRARIGFLLD
VGLSYLTLDR TAKTLSGGEA QRIRLATQIG SQLMNVMYIL DEPSIGLHQR DNDRLINALK
NLRDLGNTVL VVEHDKDMIL EADHVIDMGP AAGVHGGQVV AQGTPAQLMK EHTLTTSYLN
GERAIAVPEK RREGNGKSVI LKKATGHNLK KVTVEFPLGK LIGVTGVSGS GKSSLITETL
YPILNHHFFR AKKHPLPYEK IEGLEHIDKV IEIDQSPIGR TPRSNPATYT GVFSDIRNLY
VALPESKIRG YKPGRFSFNV KGGRCETCQG AGMKVIEMNF LPDVQVPCEE CNGRRYNRET
LEVRYRGKSI SDVLDMSIED ACPFFEHIPS IHRKIQTLQD VGLGYITLGQ SSTTLSGGEA
QRVKLATELS KKDTGNTFYI LDEPTTGLHF EDINVLLGVI NLLVDKGNTV LVIEHNLDVI
KVADHVIDLG PEGGAGGGKI LFEGTPEGLC KVKDSFTGMF LKKEMDLTAK QKKR
//
