ID H1Z1P6_9EURY Unreviewed; 706 AA.
AC H1Z1P6;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Replicative DNA helicase Mcm {ECO:0000313|EMBL:EHQ34572.1};
DE EC=3.6.1.- {ECO:0000313|EMBL:EHQ34572.1};
GN ORFNames=Metlim_0433 {ECO:0000313|EMBL:EHQ34572.1};
OS Methanoplanus limicola DSM 2279.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanomicrobiaceae; Methanoplanus.
OX NCBI_TaxID=937775 {ECO:0000313|EMBL:EHQ34572.1, ECO:0000313|Proteomes:UP000005741};
RN [1] {ECO:0000313|EMBL:EHQ34572.1, ECO:0000313|Proteomes:UP000005741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2279 {ECO:0000313|EMBL:EHQ34572.1,
RC ECO:0000313|Proteomes:UP000005741};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Lu M.,
RA Kyrpides N., Mavromatis K., Ivanova N., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Wirth R., Brambilla E.-M., Klenk H.-P.,
RA Eisen J.A.;
RT "The Improved High-Quality Draft genome of Methanoplanus limicola DSM
RT 2279.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the MCM family. {ECO:0000256|ARBA:ARBA00008010,
CC ECO:0000256|RuleBase:RU004070}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM001436; EHQ34572.1; -; Genomic_DNA.
DR RefSeq; WP_004076211.1; NZ_CM001436.1.
DR AlphaFoldDB; H1Z1P6; -.
DR STRING; 937775.Metlim_0433; -.
DR PATRIC; fig|937775.9.peg.509; -.
DR HOGENOM; CLU_000995_6_0_2; -.
DR InParanoid; H1Z1P6; -.
DR OrthoDB; 6747at2157; -.
DR Proteomes; UP000005741; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0032508; P:DNA duplex unwinding; IEA:InterPro.
DR Gene3D; 2.20.28.10; -; 1.
DR Gene3D; 3.30.1640.10; mini-chromosome maintenance (MCM) complex, chain A, domain 1; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR001208; MCM_dom.
DR InterPro; IPR041562; MCM_lid.
DR InterPro; IPR033762; MCM_OB.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR PANTHER; PTHR11630:SF43; DNA REPLICATION LICENSING FACTOR MCM6; 1.
DR Pfam; PF00493; MCM; 1.
DR Pfam; PF17855; MCM_lid; 1.
DR Pfam; PF17207; MCM_OB; 1.
DR PRINTS; PR01657; MCMFAMILY.
DR SMART; SM00350; MCM; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50051; MCM_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004070};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004070};
KW Helicase {ECO:0000313|EMBL:EHQ34572.1};
KW Hydrolase {ECO:0000313|EMBL:EHQ34572.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004070};
KW Reference proteome {ECO:0000313|Proteomes:UP000005741}.
FT DOMAIN 286..493
FT /note="MCM"
FT /evidence="ECO:0000259|PROSITE:PS50051"
SQ SEQUENCE 706 AA; 79527 MW; C411C429A51048BF CRC64;
MAEENSANVT DKAGDWTRFL KKHYKAELSE IAREFPHKRS VVIDYRQLEK WGKKGLSLAD
EILKNPGKVI GDVRDAIKNN NLIFTKDEEE KADEVNIRFI GLPKKIAARE IRANHINTFI
SIEGIVRKVT EVRPRLTSAV FRCLTCGTMT PPYKQGYGKF QEPYRPCEQC ERATKMELVP
SLSKFLDVQK VRMQESPEGL RGGEQPETID VDITDDLVAI AAPGDRIVIN GILRSIQRVT
HGNKSSLFDI YLEANSLEMS EKEFEEVAIS EEDEEHIMEL SRDSDLYYKF AHSIAPSIYG
NDEVKEAISL ILFGGIMKEL PDGSHLRGDI HMLLVGDPGI AKSQMLRYVI RLSPRGIYTS
GKSSTSAGLT ATAVKDEFGD GRWTLEAGAL VLADMGIAAV DEMDKMAKDD RSALHEAMEQ
QSISIAKAGI TATLRSRCAL LGAANPKMGR FDEFAPMSEQ INMPPSLLSR FDLIFVMKDK
PNNTLDRAIG EHILKAHEVG ELIEHTKKEA IEGVDAEYIE RALAPVTPDI DPALFRKYIA
YSKRNCFPLL SKEAKEKLID YYLSLRGFAD DNKPVPVTAR QLEALVRLSE ASARVRLSKK
IETEDAERVI RIVDRCLRDV AYDPNTESFD IDKLVTGIPK QRRDIIREIK ETIRNNADDN
GYTRIEEVQE ILQQKGHSKD DIRKRLDDLL RSGEAMEPRH GIIKLI
//
