ID H2AMQ6_KAZAF Unreviewed; 511 AA.
AC H2AMQ6;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 13-SEP-2023, entry version 58.
DE RecName: Full=TrmE-type G domain-containing protein {ECO:0000259|PROSITE:PS51709};
GN Name=KAFR0A02180 {ECO:0000313|EMBL:CCF55656.1};
GN ORFNames=KAFR_0A02180 {ECO:0000313|EMBL:CCF55656.1};
OS Kazachstania africana (strain ATCC 22294 / BCRC 22015 / CBS 2517 / CECT
OS 1963 / NBRC 1671 / NRRL Y-8276) (Yeast) (Kluyveromyces africanus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kazachstania.
OX NCBI_TaxID=1071382 {ECO:0000313|EMBL:CCF55656.1, ECO:0000313|Proteomes:UP000005220};
RN [1] {ECO:0000313|EMBL:CCF55656.1, ECO:0000313|Proteomes:UP000005220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 /
RC NRRL Y-8276 {ECO:0000313|Proteomes:UP000005220};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. TrmE GTPase family. {ECO:0000256|ARBA:ARBA00011043,
CC ECO:0000256|RuleBase:RU003313}.
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DR EMBL; HE650821; CCF55656.1; -; Genomic_DNA.
DR RefSeq; XP_003954791.1; XM_003954742.1.
DR AlphaFoldDB; H2AMQ6; -.
DR STRING; 1071382.H2AMQ6; -.
DR GeneID; 13882289; -.
DR KEGG; kaf:KAFR_0A02180; -.
DR eggNOG; KOG1191; Eukaryota.
DR HOGENOM; CLU_019624_3_1_1; -.
DR InParanoid; H2AMQ6; -.
DR OrthoDB; 5478664at2759; -.
DR Proteomes; UP000005220; Chromosome 1.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0006400; P:tRNA modification; IEA:InterPro.
DR CDD; cd04164; trmE; 1.
DR CDD; cd14858; TrmE_N; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.120.430; tRNA modification GTPase MnmE domain 2; 1.
DR HAMAP; MF_00379; GTPase_MnmE; 1.
DR InterPro; IPR031168; G_TrmE.
DR InterPro; IPR006073; GTP-bd.
DR InterPro; IPR018948; GTP-bd_TrmE_N.
DR InterPro; IPR004520; GTPase_MnmE.
DR InterPro; IPR027368; MnmE_dom2.
DR InterPro; IPR025867; MnmE_helical.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR NCBIfam; TIGR00450; mnmE_trmE_thdF; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42714; TRNA MODIFICATION GTPASE GTPBP3; 1.
DR PANTHER; PTHR42714:SF2; TRNA MODIFICATION GTPASE GTPBP3, MITOCHONDRIAL; 1.
DR Pfam; PF01926; MMR_HSR1; 1.
DR Pfam; PF12631; MnmE_helical; 1.
DR Pfam; PF10396; TrmE_N; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51709; G_TRME; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU003313};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU003313};
KW Reference proteome {ECO:0000313|Proteomes:UP000005220};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694,
KW ECO:0000256|RuleBase:RU003313}.
FT DOMAIN 258..429
FT /note="TrmE-type G"
FT /evidence="ECO:0000259|PROSITE:PS51709"
SQ SEQUENCE 511 AA; 57092 MW; 7D18B37BDD04E5C8 CRC64;
MMLPITFPLS TGKMRLYSRL VKPLTSNFPT IYALSTPTGH KSAISVIRIS GSHAKYIYHK
LTRCSADPIP REAVLRKLYH PFEIINNKPL LLDSSLILFF QSPKSFTGED ILELHVHGGR
AIVSSVLNAI NLLHDRSSNF NIRYAQPGEF SKRAFHNSKF DLTEVEAIND LINADTEAQR
RSILSSLNGD NKLLFREWRS LLITCMAQLT AIIDFGDDND LSTSHDIIKG VSNKILGLKN
KVIDFINKVE RADILNDGIK IVFMGSPNVG KSSLLNMVTN DDTSIVSDIP GTTRDSVSTL
INIGGQKIIM TDTAGIRKES NDKIELLGIE RAKEKSGKSD ICILVLDPTR NVILDAEVIS
WVKSLYGRKK EILVVLNKSD LFEDKKILES IKRDVCSSFK GLDFPIITTS SKTSSGVKAF
FTVLKEKTEK ISFLNKHSEA ITISMRAKEI LRKDVLYGIN EFLKSNNDRH DLIILSENLQ
YSIDGISKIT GEHVDVEEIL DAVFSKFCIG K
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