ID H2AS34_KAZAF Unreviewed; 1020 AA.
AC H2AS34;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE RecName: Full=STAS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=KAFR0C01910 {ECO:0000313|EMBL:CCF57184.1};
GN ORFNames=KAFR_0C01910 {ECO:0000313|EMBL:CCF57184.1};
OS Kazachstania africana (strain ATCC 22294 / BCRC 22015 / CBS 2517 / CECT
OS 1963 / NBRC 1671 / NRRL Y-8276) (Yeast) (Kluyveromyces africanus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kazachstania.
OX NCBI_TaxID=1071382 {ECO:0000313|EMBL:CCF57184.1, ECO:0000313|Proteomes:UP000005220};
RN [1] {ECO:0000313|EMBL:CCF57184.1, ECO:0000313|Proteomes:UP000005220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 /
RC NRRL Y-8276 {ECO:0000313|Proteomes:UP000005220};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; HE650823; CCF57184.1; -; Genomic_DNA.
DR RefSeq; XP_003956319.1; XM_003956270.1.
DR AlphaFoldDB; H2AS34; -.
DR STRING; 1071382.H2AS34; -.
DR GeneID; 13885582; -.
DR KEGG; kaf:KAFR_0C01910; -.
DR eggNOG; KOG0236; Eukaryota.
DR HOGENOM; CLU_003182_0_2_1; -.
DR InParanoid; H2AS34; -.
DR OrthoDB; 204198at2759; -.
DR Proteomes; UP000005220; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR PANTHER; PTHR43310:SF4; SULFATE TRANSPORTER; 1.
DR PANTHER; PTHR43310; SULFATE TRANSPORTER YBAR-RELATED; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005220};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 210..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..402
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 467..490
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 510..530
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 550..583
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 603..631
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 210..608
FT /note="SLC26A/SulP transporter"
FT /evidence="ECO:0000259|Pfam:PF00916"
FT DOMAIN 671..778
FT /note="STAS"
FT /evidence="ECO:0000259|Pfam:PF01740"
SQ SEQUENCE 1020 AA; 115201 MW; 55D24A401947AEA4 CRC64;
MTSFNKSNDA RASKRLSLSD SISRSLGLQD QESNIAGTDN ELSNSKSNYL SRSYMYGLLP
SATPVEELET NTLPLSNDLR NKSIHQSRIL HKQTAAICED FNESDEGSMK DYLDFIENTD
RDNINEHKES LPVTVVLSTP ADEVEEQDES SRLLLTPSSS NAEVSSIAEG LRHHYSSIES
TKDNNMPIEE QQDNTINEKL STFFYNTLQY FPASVLGLLL NILDALSYGM IIFPISEPIF
SHLGPTGMSM FYISTIICQF IYSSGWSSFP SCIGSEMIEI TPFFHTMAFA IMRSLPGEEN
QDAIITTTIF CYVISSMFTG LTFLTLGKLR LGKIVGFFPR HILIGCIGGV GYFLLITGIE
VTTRIAKFEY SLPLIKELFT DTSMLWKWLT PTLLTVVLIL TQKCFKRSLV LPSFYIATLI
LFHFIVAIIP RLSLTQLREA GWIFSNTAPN SAWYDHYKLF DFHKVHWLLV FKQIPTMLAL
TFFGILHVPI NVPALAMSVQ MDKYDVDKEL IAHGLSNLVS GMFGSIQNYL VYTNSVLFIR
AGADSPFAGY LLIFLTIVVM LIGPVIISFI PICIVGSLIF LLGYELLVEA LLDTWDKLTT
FEYVTVVVIV LTMGIVDFVL GIIVGILIAC FKFLIDSSKL QTINGEFSGK VAKSTVNRDL
IQSKFLNGIG DQIYVLKLQN LLFFGTIISI EEKIDKLLEM SDRNSSKRQI KYLILDFRNI
NADNIDYSAA EGFNRIKRLT ESKNIQLIIS SIKVRDRIYN SFNKVGLLVG VELFNDLNGA
LEWCENEFLY QYKMIRERIK IKNVKTATHS SDGNLSKPSA MTLSINTPRN YQIYSVAQNI
FKNEEQTVDR LKNRFQDQTP VLPLLLFALK QYRPDIVSVD KVKKGKEIEF WSQLAPYFSK
KRIASQSILY HGNNIFFLVE IGVLKVTFDL PQGKVYETMS KRACYGKIMG KIPVSEADAP
SSQAMIIKTE ADTVIWIIDS SALKKMKDEN IELYLELVLL VMTIKDIRFK SLLGHALVST
//
