ID H2ASW5_KAZAF Unreviewed; 665 AA.
AC H2ASW5;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Transcriptional repressor Tup1 N-terminal domain-containing protein {ECO:0000259|Pfam:PF08581};
GN Name=KAFR0C04740 {ECO:0000313|EMBL:CCF57465.1};
GN ORFNames=KAFR_0C04740 {ECO:0000313|EMBL:CCF57465.1};
OS Kazachstania africana (strain ATCC 22294 / BCRC 22015 / CBS 2517 / CECT
OS 1963 / NBRC 1671 / NRRL Y-8276) (Yeast) (Kluyveromyces africanus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kazachstania.
OX NCBI_TaxID=1071382 {ECO:0000313|EMBL:CCF57465.1, ECO:0000313|Proteomes:UP000005220};
RN [1] {ECO:0000313|EMBL:CCF57465.1, ECO:0000313|Proteomes:UP000005220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 /
RC NRRL Y-8276 {ECO:0000313|Proteomes:UP000005220};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
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DR EMBL; HE650823; CCF57465.1; -; Genomic_DNA.
DR RefSeq; XP_003956600.1; XM_003956551.1.
DR AlphaFoldDB; H2ASW5; -.
DR STRING; 1071382.H2ASW5; -.
DR GeneID; 13885383; -.
DR KEGG; kaf:KAFR_0C04740; -.
DR eggNOG; KOG0266; Eukaryota.
DR HOGENOM; CLU_000288_57_23_1; -.
DR InParanoid; H2ASW5; -.
DR OrthoDB; 91476at2759; -.
DR Proteomes; UP000005220; Chromosome 3.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.5.340; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR013890; Tscrpt_rep_Tup1_N.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR44129:SF1; PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT BETA; 1.
DR PANTHER; PTHR44129; WD REPEAT-CONTAINING PROTEIN POP1; 1.
DR Pfam; PF08581; Tup_N; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 5.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 5.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000005220};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 11..88
FT /note="Transcriptional repressor Tup1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08581"
FT REPEAT 379..420
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 421..462
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 462..504
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 512..553
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 568..609
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 91..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 142..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 182..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 353..377
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 9..36
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 665 AA; 72230 MW; 7BEB4F5E8D112C42 CRC64;
MSTAAAASQN KLNELLEAIR QEFANVSQEA NTYRLQNQKD YDYKINQHLA EMQQIRNTVY
ELELSHRKLK DSYQEEINRL KLELNQKDQQ IASLSQHAQS HVPSTTNTTT SAPQDSATMS
TANVATATPN VAVTANITGQ AAGSASLPQP NTAATPGTAT NTNGPTLAPL ISALGSQLQP
LQVPGQQQQV PPQQPAAQLQ QQVPEATTQQ YQPAVAAAAP VVAAPTVTEP QDQATKPKEE
VEKNDKEHYL VPFDQRASQL KAIPPFLLDL DAQQVPAHLK KLAEDYYILY NPALPRNLDV
ELHASLDHSS VVCCVKFSND GEYLATGCNK TSQIYKVSTG ELIAKLSDDN ANSAVSSNNN
DQNAPANVNG ANANSGNNTN SNDLYIRSVC FSPDGKFLAT GAEDKLIRIW DIQQRKIVMV
LQGHDQDVYS LDYFPSGDKL VSGSGDRTVR IWDLKTGQCS LTLSIEDGVT TVAVSPGDGK
FIAAGSLDRA VRVWDSETGF LVERLDSENE LGTGHKDSVY SVVFTKDGNK VVSGSLDRSV
KLWNLRDNNA NSSSNNSNKS NATCDVTYVG HKDFVLSVTT TANDEYILSG SKDRGVLFWD
TKSGNPLLML QGHRNSVISV AVANRTPLGP KYQVFATGSG DCRARIWKFS KIDDTENSEN
KITEV
//
