ID H2B093_KAZAF Unreviewed; 1091 AA.
AC H2B093;
DT 21-MAR-2012, integrated into UniProtKB/TrEMBL.
DT 21-MAR-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=TOG domain-containing protein {ECO:0000259|SMART:SM01349};
GN Name=KAFR0I02640 {ECO:0000313|EMBL:CCF60043.1};
GN ORFNames=KAFR_0I02640 {ECO:0000313|EMBL:CCF60043.1};
OS Kazachstania africana (strain ATCC 22294 / BCRC 22015 / CBS 2517 / CECT
OS 1963 / NBRC 1671 / NRRL Y-8276) (Yeast) (Kluyveromyces africanus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kazachstania.
OX NCBI_TaxID=1071382 {ECO:0000313|EMBL:CCF60043.1, ECO:0000313|Proteomes:UP000005220};
RN [1] {ECO:0000313|EMBL:CCF60043.1, ECO:0000313|Proteomes:UP000005220}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 /
RC NRRL Y-8276 {ECO:0000313|Proteomes:UP000005220};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; HE650829; CCF60043.1; -; Genomic_DNA.
DR RefSeq; XP_003959178.1; XM_003959129.1.
DR AlphaFoldDB; H2B093; -.
DR STRING; 1071382.H2B093; -.
DR GeneID; 13883679; -.
DR KEGG; kaf:KAFR_0I02640; -.
DR eggNOG; KOG2171; Eukaryota.
DR HOGENOM; CLU_003794_0_1_1; -.
DR InParanoid; H2B093; -.
DR OrthoDB; 24319at2759; -.
DR Proteomes; UP000005220; Chromosome 9.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 6.10.140.1700; -; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR040122; Importin_beta.
DR InterPro; IPR041653; Importin_rep_4.
DR InterPro; IPR040928; Importin_rep_5.
DR InterPro; IPR041389; Importin_rep_6.
DR InterPro; IPR034085; TOG.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR PANTHER; PTHR10527:SF5; IMPORTIN-5 ISOFORM X1; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR Pfam; PF18808; Importin_rep_4; 1.
DR Pfam; PF18816; Importin_rep_5; 1.
DR Pfam; PF18829; Importin_rep_6; 1.
DR SMART; SM01349; TOG; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005220};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 349..598
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
SQ SEQUENCE 1091 AA; 121613 MW; A9A278152E8E2538 CRC64;
MSTSQGYQDA LIEILQGFAS PNNEIRSAAE KSLNQNWITA ENIEPLLIFL AEQASLSQDL
TIAALSAVLF RKLALRAPPS SKTVIIAKNI SHISENALLH IRSTLLKGFV CERPKDIRHK
LSDAISECAI EELPAWPELL QAIVEFLKNQ DPIFRESSFR ILASVPHLIN AVDVANVLPV
FEAGFTDAND EVKISAVTAF VGYFKQLPKV HWSNIGVLLP SLLNSLPKFL DDNKDDALAS
VFESLIELVE LAPRLFKGMF DQIIQFSDIV IKNKDLETHA RTTALELLTV FSENAPQMCK
SNPNYSQSLV MNTLLMMTEV SFDDDEASEW RESDDTEDEE EVTYDHARQS LDRVSLKLGG
EYLAPTLFQY LQQMVKSSEW RERFAAMMAL SSAAEGCQDV LIGEIPKILD MVISLINDPH
PRVQYGCCNV LGQISTDFAP LIQRTSHDRI VPALISKLTP ESLDRVQTHA AAALVNFSEQ
ANQGILEPYL DSLLTNLLTL LQSNKLYVQE QALTTIAFIA EAAKTKFIKY YDTLMPLLLN
VLKMENVDSN GVLKGKCIEC ATLIAAAVGK QKFSEHSQEL INLLLAHQSN SVDDENESIR
SYLEHGWGRI CKILGADFVP LLPVVLPPLL ETAKATQDVS LIEEEEAAEF QKYSEWDVVQ
IQGKHIAIHT SILDDKVSAM ELLQLYASIL KERFANYVKE ILSEIAIPAI DFYLHDGVRA
TGASLIPILL NCLVSASGSQ NEEILQLWQF ASAKLIGGIN TEPMLEITQA YHTALVDGMT
VMSNVSLNEE LLPQYVKGVT NNLSDVFERI KERHNEADEY NEGLDDELDE FTDEDLLDEI
NKSLSSIMKT SGQTFLPYIQ IIWPLIQTYL QDTEVILLLF SLVAIGDIIQ YYGDVTASFK
DSFIEKVKSF LVSPEPQLRQ ASAYIIGVCA QFAPNTYGEI CVSSLETLLQ VINIPEAKNE
ENQSATENAS AAIAKILYAF NSNIPKVDEY TSTWFKSLPT TVDEEAASFN YMYLSHLIDS
NSPIICEPSN IPIIVNNVVL ALHHKSIGGK TAELVVGSLK KLLSTLPQND AMAMLQRYPD
DYMQTIQRWF S
//
